Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 10/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 9/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | USP19 | O94966 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13705411 | 1.00 | HCRTR1 (0.43) | HCRTR1HCRTR2CHRM3FFAR1PPARD | |
| SCHEMBL4281562 | 0.97 | HCRTR1 (0.44) | HCRTR1HCRTR2CHRM3FFAR1PPARD | |
| SCHEMBL13705418 | 0.95 | HCRTR1 (0.42) | HCRTR1HCRTR2CHRM3CHEK2USP19 | |
| SCHEMBL8118892 | 0.95 | HCRTR1 (0.42) | HCRTR1HCRTR2CHRM3CHEK2USP19 | |
| SCHEMBL13705466 | 0.95 | HCRTR1 (0.41) | HCRTR1HCRTR2CHRM3CHEK2USP19 | |
| SCHEMBL13705419 | 0.93 | HCRTR1 (0.40) | HCRTR1HCRTR2CHEK2 | |
| SCHEMBL8126947 | 0.93 | HCRTR1 (0.40) | HCRTR1HCRTR2CHEK2 | |
| SCHEMBL13705473 | 0.93 | HCRTR1 (0.40) | HCRTR1HCRTR2CHRM3CHEK2USP19 | |
| SCHEMBL4287699 | 0.92 | HCRTR1 (0.43) | HCRTR1HCRTR2KDM1ACHEK2 | |
| SCHEMBL13705420 | 0.91 | HCRTR1 (0.41) | HCRTR1HCRTR2CHRM3CHEK2USP19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |