Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | CD40 | P25942 | 1/20 | 0.37 |
| ▸ | CD40LG | P29965 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 8/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7778365 | 1.00 | NT5E (0.40) | NT5ECD40CD40LGCYP1A2ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL10350739 | 0.85 | NT5E (0.43) | NT5ECD40CD40LGCYP1A2ALDH1A1 | |
| SCHEMBL6030186 | 0.83 | NT5E (0.41) | NT5ECD40CD40LGCYP1A2ALDH1A1 | |
| SCHEMBL4699280 | 0.83 | NT5E (0.41) | NT5ECD40CD40LGCYP1A2ALDH1A1 | |
| SCHEMBL9238793 | 0.83 | NT5E (0.41) | NT5ECD40CD40LGCYP1A2ALDH1A1 | |
| SCHEMBL10350681 | 0.82 | NT5E (0.41) | NT5ECD40CD40LGCYP1A2ALDH1A1 | |
| SCHEMBL9238781 | 0.82 | NT5E (0.41) | NT5ECD40CD40LGCYP1A2ALDH1A1 | |
| SCHEMBL10350679 | 0.82 | NT5E (0.41) | NT5ECD40CD40LGCYP1A2ALDH1A1 | |
| SCHEMBL13302234 | 0.81 | NT5E (0.47) | NT5ECD40CD40LGALDH1A1MEN1 | |
| SCHEMBL6747120 | 0.77 | NT5E (0.41) | NT5ECD40CD40LGCYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0576143-B1 | Reactive dyes containing a 2,6-difluoro-3,5-dichloropyridine-4-ylamino group | BASF AG (DE) | 2000-08-09 | — | — | EP | disclosed |
| US-5373094-A | Reactive dyes containing a 2,6-difluoro-3,5-dichloropyridine group | ZENECA LIMITED (GB) | 1994-12-13 | — | — | US | disclosed |
| EP-0576143-A2 | Reactive dyes containing a 2,6-difluoro-3,5-dichloropyridine-4-ylamino group | ZENECA LIMITED (GB) | 1993-12-29 | — | — | EP | disclosed |