SCHEMBL8125367

SCHEMBL8125367

OC[C@@H]1C=CCCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1171442 1.00
SCHEMBL10516123 1.00
Cyclohexene SCHEMBL8591210 0.95
SCHEMBL8585997 0.93
SCHEMBL11045942 0.91
SCHEMBL11045946 0.91
SCHEMBL259931 0.84
SCHEMBL19002827 0.84
SCHEMBL17724661 0.84
SCHEMBL21980551 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2013167-B1 TOTAL SYNTHESIS OF SALINOSPORAMIDE A AND ANALOGS THEREOF NEREUS PHARMACEUTICALS INC (US) 2012-09-05 EP disclosed
EP-2266988-A1 [3.2.0] Heterocyclic compounds and methods of using the same Nereus Pharmaceuticals, Inc. (US) 2010-12-29 EP disclosed
EP-2025679-A2 [3.2.0] Heterocyclic compounds and methods of using the same Nereus Pharmaceuticals, Inc. (US) 2009-02-18 EP disclosed
WO-2008137780-A2 USE OF [3.2.0] HETEROCYCLIC COMPOUNDS AND ANALOGS THEREOF FOR TREATING INFECTIOUS DISEASES NEREUS PHARMACEUTICALS, INC. (US) 2008-11-13 WO disclosed
WO-2007117591-A9 TOTAL SYNTHESIS OF SALINOSPORAMIDE A AND ANALOGS THEREOF NEREUS PHARMACEUTICALS INC (US) 2008-10-02 WO disclosed
EP-1749830-A1 CURCUMOL DERIVATIVES, THE COMPOSITIONS COMPRISING THE SAME AND THE USE OF THE SAME IN THE MANUFACTURE OF MEDICAMENT Hangzhou Minsheng Pharmaceuticals Co., Ltd. (CN) 2007-02-07 EP disclosed