Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | EPOR | P19235 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8120051 | 0.92 | EPOR (0.34) | KDM4ENLRP3ALDH1A1KMT2AMEN1 | |
| SCHEMBL27516787 | 0.79 | NPY4R (0.37) | — | |
| SCHEMBL7751685 | 0.79 | NPY4R (0.37) | — | |
| SCHEMBL7750620 | 0.77 | KMT2A (0.41) | KDM4EALDH1A1KMT2AMEN1EPOR | |
| SCHEMBL9195398 | 0.72 | KMT2A (0.41) | KDM4EALDH1A1KMT2AMEN1EPOR | |
| SCHEMBL8120666 | 0.71 | NPY4R (0.35) | EPOR | |
| SCHEMBL8121285 | 0.69 | EPOR (0.41) | KMT2AMEN1EPOR | |
| SCHEMBL6901612 | 0.68 | CNR1 (0.43) | ALDH1A1KMT2A | |
| SCHEMBL8124054 | 0.68 | HRH3 (0.39) | KDM4EALDH1A1EPOR | |
| SCHEMBL4651831 | 0.67 | CNR1 (0.42) | KMT2AMEN1EPOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |