Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 3/20 | 0.39 |
| ▸ | EPOR | P19235 | 4/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | MC4R | P32245 | 2/20 | 0.31 |
| ▸ | MC5R | P33032 | 2/20 | 0.31 |
| ▸ | MC3R | P41968 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8121861 | 0.93 | EPOR (0.35) | CALCRLEPORTACR1MEN1KMT2A | |
| SCHEMBL4651776 | 0.86 | CNR1 (0.35) | CALCRLEPORTACR1 | |
| SCHEMBL1388307 | 0.85 | CNR1 (0.35) | CALCRLTACR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8118676 | 0.84 | CNR1 (0.35) | CALCRLTACR1MEN1KMT2A | |
| SCHEMBL8650060 | 0.84 | TDP1 (0.41) | EPORMEN1KMT2ATDP1TRPM8 | |
| SCHEMBL9196210 | 0.84 | TACR1 (0.36) | EPORTACR1MEN1KMT2ATDP1 | |
| SCHEMBL8119409 | 0.84 | EPOR (0.43) | EPORMEN1KMT2ATDP1MC4R | |
| SCHEMBL8119338 | 0.82 | MAPT (0.38) | MEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL8120628 | 0.82 | EPOR (0.41) | EPORMEN1KMT2ATDP1MC4R | |
| SCHEMBL8126608 | 0.80 | TDP1 (0.41) | EPORMEN1KMT2ATDP1MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |