Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.65 |
| ▸ | PKM | P14618 | 2/20 | 0.65 |
| ▸ | MITF | O75030 | 1/20 | 0.65 |
| ▸ | PPARG | P37231 | 14/20 | 0.54 |
| ▸ | PPARA | Q07869 | 12/20 | 0.54 |
| ▸ | PPARD | Q03181 | 7/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955885 | 0.91 | NPC1 (0.61) | NPC1RAB9APKMMITFPPARG | |
| SCHEMBL6947575 | 0.90 | PPARG (0.63) | NPC1RAB9APKMMITFPPARG | |
| SCHEMBL8125999 | 0.90 | NPC1 (0.59) | NPC1RAB9APKMMITFPPARG | |
| SCHEMBL8123923 | 0.90 | NPC1 (0.62) | NPC1RAB9APKMMITFPPARG | |
| SCHEMBL8126657 | 0.89 | NPC1 (0.61) | NPC1RAB9APKMMITFPPARG | |
| SCHEMBL8126626 | 0.89 | NPC1 (0.63) | NPC1RAB9APKMMITFPPARG | |
| SCHEMBL8117033 | 0.87 | NPC1 (0.69) | NPC1RAB9APKMMITFPPARG | |
| SCHEMBL6956761 | 0.86 | NPC1 (0.62) | NPC1RAB9APKMMITFPPARG | |
| SCHEMBL6955730 | 0.86 | NPC1 (0.62) | NPC1RAB9APKMMITFPPARG | |
| SCHEMBL6956847 | 0.85 | NPC1 (0.67) | NPC1RAB9APKMMITFPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051403-A1 | NOVEL ALKANOIC ACIDS AND THEIR USE IN MEDICINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-11-15 | — | — | EP | claimed |
| WO-1999038850-A1 | NOVEL ALKANOIC ACIDS AND THEIR USE IN MEDICINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-08-05 | — | — | WO | claimed |