Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.90 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.90 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | DRD3 | P35462 | 2/20 | 0.56 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.56 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.55 |
| ▸ | APP | P05067 | 4/20 | 0.55 |
| ▸ | SNCA | P37840 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.55 |
| ▸ | RXRA | P19793 | 5/20 | 0.50 |
| ▸ | RARA | P10276 | 4/20 | 0.50 |
| ▸ | RARB | P10826 | 4/20 | 0.50 |
| ▸ | RARG | P13631 | 4/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8132702 | 1.00 | MAPT (0.90) | MAPTALOX15ALDH1A1PTGS1LMNA | |
| Canthaxanthin SCHEMBL12920083 | 0.95 | MAPT (1.00) | MAPTALOX15ALDH1A1PTGS1LMNA | |
| Canthaxanthin SCHEMBL19618 | 0.95 | MAPT (1.00) | MAPTALOX15ALDH1A1PTGS1LMNA | |
| Canthaxanthin SCHEMBL8971840 | 0.95 | MAPT (1.00) | MAPTALOX15ALDH1A1PTGS1LMNA | |
| SCHEMBL2878712 | 0.91 | MAPT (0.87) | MAPTALOX15ALDH1A1PTGS1LMNA | |
| SCHEMBL2832602 | 0.91 | MAPT (0.92) | MAPTALOX15ALDH1A1PTGS1LMNA | |
| SCHEMBL2398379 | 0.91 | MAPT (0.87) | MAPTALOX15ALDH1A1PTGS1LMNA | |
| Canthaxanthin SCHEMBL419514 | 0.90 | MAPT (0.90) | MAPTALOX15ALDH1A1PTGS1LMNA | |
| SCHEMBL13252665 | 0.90 | MAPT (0.90) | MAPTALOX15ALDH1A1PTGS1LMNA | |
| SCHEMBL12646769 | 0.88 | MAPT (0.85) | MAPTALOX15ALDH1A1PTGS1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630578-B1 | Pigmentation with carotenoids | HOFFMANN LA ROCHE (CH) | 2000-05-31 | — | — | EP | claimed |
| EP-0630578-A2 | Pigmentation with carotenoids | F. HOFFMANN-LA ROCHE AG (CH) | 1994-12-28 | — | — | EP | claimed |
| EP-0630578-B1 | Pigmentation with carotenoids | HOFFMANN LA ROCHE (CH) | 2000-05-31 | — | — | EP | disclosed |
| US-5670548-A | USED IN FOODS | ROCHE VITAMINS INC. (US) | 1997-09-23 | — | — | US | disclosed |
| US-5605699-A | FOR USE IN ANIMAL FEEDS; FOR ENHANCING COLOR OF EGG YOLKS | HOFFMANN-LA ROCHE INC. (US) | 1997-02-25 | — | — | US | disclosed |
| EP-0630578-A2 | Pigmentation with carotenoids | F. HOFFMANN-LA ROCHE AG (CH) | 1994-12-28 | — | — | EP | disclosed |