Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 14/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8130711 | 0.90 | PTPN1 (0.49) | PPARGPTPN1PPARAFFAR1KDR | |
| SCHEMBL8794339 | 0.86 | FFAR1 (0.60) | PPARGPPARAFFAR1KDR | |
| SCHEMBL8795246 | 0.85 | KDR (0.59) | PPARGPPARAFFAR1KDR | |
| SCHEMBL8130824 | 0.85 | PTPN1 (0.49) | PPARGPTPN1PPARAFFAR1KDR | |
| SCHEMBL7162936 | 0.83 | FFAR1 (0.59) | PPARGPPARAFFAR1KDR | |
| SCHEMBL7164834 | 0.82 | FFAR1 (0.58) | PPARGPPARAFFAR1KDR | |
| SCHEMBL8795234 | 0.82 | FFAR1 (0.62) | PPARGPPARAFFAR1KDR | |
| SCHEMBL6052186 | 0.81 | PPARG (0.58) | PPARGPPARAFFAR1KDR | |
| SCHEMBL8133574 | 0.81 | KDR (0.59) | PPARGPTPN1PPARAFFAR1KDR | |
| SCHEMBL8793334 | 0.79 | PPARG (0.55) | PPARGPPARAFFAR1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733631-B1 | Benzofuran derivates useful as hypoglycemic and hypolidemic agents | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-07-12 | — | — | EP | claimed |
| EP-0733631-A1 | Benzofuran derivates useful as hypoglycemic and hypolidemic agents | Takeda Chemical Industries, Ltd. (JP) | 1996-09-25 | — | — | EP | claimed |
| EP-0733631-B1 | Benzofuran derivates useful as hypoglycemic and hypolidemic agents | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-07-12 | — | — | EP | disclosed |
| EP-0733631-A1 | Benzofuran derivates useful as hypoglycemic and hypolidemic agents | Takeda Chemical Industries, Ltd. (JP) | 1996-09-25 | — | — | EP | disclosed |