Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 12/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 10/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 9/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 9/20 | 0.37 |
| ▸ | IARS1 | P41252 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8119566 | 0.85 | DPP4 (0.39) | DPP4DPP8DPP9DPP7IARS1 | |
| SCHEMBL8120903 | 0.82 | DPP4 (0.37) | DPP4DPP8DPP9DPP7IARS1 | |
| SCHEMBL8121069 | 0.81 | DPP4 (0.36) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL7779224 | 0.80 | DPP4 (0.43) | DPP4DPP8DPP9DPP7IARS1 | |
| SCHEMBL21105595 | 0.80 | DPP4 (0.43) | DPP4DPP8DPP9DPP7IARS1 | |
| SCHEMBL7779225 | 0.80 | DPP4 (0.43) | DPP4DPP8DPP9DPP7IARS1 | |
| SCHEMBL8129730 | 0.80 | SLC7A5 (0.41) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL17833218 | 0.79 | DPP4 (0.37) | DPP4DPP8DPP9DPP7IARS1 | |
| SCHEMBL17833245 | 0.79 | DPP4 (0.37) | DPP4DPP8DPP9DPP7IARS1 | |
| SCHEMBL17833081 | 0.79 | DPP4 (0.37) | DPP4DPP8DPP9DPP7IARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054891-A1 | PRODRUGS | MEDIVIR AB (SE) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999041275-A1 | PRODRUGS | MEDIVIR AB (SE) | 1999-08-19 | — | — | WO | disclosed |