Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.68 |
| ▸ | CHRM2 | P08172 | 8/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.54 |
| ▸ | SCN1A | P35498 | 3/20 | 0.54 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.54 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.48 |
| ▸ | HRH1 | P35367 | 6/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.48 |
| ▸ | HTR2A | P28223 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29683764 | 0.98 | TSHR (0.66) | TSHRCHRM2SLC6A2SLC6A4SCN1A | |
| SCHEMBL2681260 | 0.83 | TSHR (0.55) | TSHRCHRM2SLC6A2SLC6A4SCN1A | |
| SCHEMBL27901208 | 0.81 | TSHR (0.68) | TSHRCHRM2SLC6A2SLC6A4SCN1A | |
| SCHEMBL15618256 | 0.80 | TSHR (0.51) | TSHRCHRM2SLC6A2SLC6A4SCN1A | |
| SCHEMBL1205713 | 0.78 | TSHR (0.68) | TSHRCHRM2SLC6A2SLC6A4SCN1A | |
| SCHEMBL6282491 | 0.78 | TSHR (0.68) | TSHRCHRM2SLC6A2SLC6A4SCN1A | |
| SCHEMBL30679621 | 0.74 | TSHR (0.57) | TSHRCHRM2SLC6A2SLC6A4SCN1A | |
| SCHEMBL18988389 | 0.74 | TSHR (0.57) | TSHRCHRM2SLC6A2SLC6A4SCN1A | |
| SCHEMBL3910230 | 0.74 | TSHR (0.62) | TSHRCHRM2SLC6A2SLC6A4SCN1A | |
| SCHEMBL16999005 | 0.74 | TSHR (0.62) | TSHRCHRM2SLC6A2SLC6A4SCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8052947-B2 | Method for selective separation of trivalent and tetravalent actinoids from trivalent lanthanoids using hybrid donor type extractant having functional group carrying active oxygen and nitrogen atoms | JAPAN ATOMIC ENERGY AGENCY (JP) | 2011-11-08 | — | — | US | disclosed |
| US-20090320646-A1 | METHOD FOR SELECTIVE SEPARATION OF TRIVALENT AND TETRAVALENT ACTINOIDS FROM TRIVALENT LANTHANOIDS USING HYBRID DONOR TYPE EXTRACTANT HAVING FUNCTIONAL GROUP CARRYING ACTIVE OXYGEN AND NITROGEN ATOMS | JAPAN ATOMIC ENERGY AGENCY (JP) | 2009-12-31 | — | — | US | disclosed |
| EP-2128871-A1 | METHOD FOR SELECTIVE SEPARATION OF TRIVALENT AND TETRAVALENT ACTINOIDS FROM TRIVALENT LANTHANOIDE USING HYBRID DONOR-TYPE EXTRACTING AGENT HAVING FUNCTIONAL GROUP CARRYING ACTIVE OXYGEN AND NITROGEN ATOMS | Japan Atomic Energy Agency (JP) | 2009-12-02 | — | — | EP | disclosed |