Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.50 |
| ▸ | FLT4 | P35916 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 1/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8131336 | 0.89 | KMT2A (0.71) | KMT2AEPHA2FLT4GSK3BRARB | |
| SCHEMBL8133502 | 0.87 | DPP4 (0.47) | KMT2AKDM4EHSD17B10LMNADPP4 | |
| SCHEMBL8133506 | 0.87 | DPP4 (0.47) | KMT2AKDM4EHSD17B10LMNADPP4 | |
| SCHEMBL10552247 | 0.86 | KMT2A (0.79) | KMT2AEPHA2FLT4GSK3BRARB | |
| SCHEMBL9603754 | 0.84 | DPP4 (0.51) | KMT2AKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL9603753 | 0.84 | DPP4 (0.51) | KMT2AKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL10547292 | 0.84 | KMT2A (0.61) | KMT2AEPHA2FLT4GSK3BRARB | |
| SCHEMBL9597618 | 0.83 | DPP4 (0.43) | KMT2AKDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL5868714 | 0.82 | KMT2A (0.66) | KMT2AEPHA2FLT4GSK3BRARB | |
| SCHEMBL9293429 | 0.82 | DPP4 (0.46) | KMT2AKDM4EHPGDALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561850-B1 | 7-SUBSTITUTED-6-FLUORO-1,4-DIHYDRO-4-OXO-QUINOLINE-3-CARBOXYLIC ACID COMPOUNDS USEFUL AS ANTIBACTERIAL AGENTS | NAEJA PHARMACEUTICAL INC (CA) | 2000-07-12 | — | — | EP | disclosed |
| US-5342846-A | 7-substituted-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid compounds and 7-(substituted triazolyl pyrrolidin-1-yl) 4-oxoquinoline-3-carboxylic acid derivatives useful as antibacterial agents | SYNPHAR LABORATORIES, INC. (CA) | 1994-08-30 | — | — | US | disclosed |
| WO-1993024481-A1 | 7-SUBSTITUTED-6-FLUORO-1,4-DIHYDRO-4-OXO-QUINOLINE-3-CARBOXYLIC ACID COMPOUNDS AND RELATED COMPOUNDS AS ANTIBACTERIAL AGENTS | SYNPHAR LABORATORIES, INC. (CA) | 1993-12-09 | — | — | WO | disclosed |
| EP-0561850-A1 | 7-SUBSTITUTED-6-FLUORO-1,4-DIHYDRO-4-OXO-QUINOLINE-3-CARBOXYLIC ACID COMPOUNDS USEFUL AS ANTIBACTERIAL AGENTS | SYNPHAR LABORATORIES INC. (CA) | 1993-09-29 | — | — | EP | disclosed |
| WO-1992010492-A1 | 7-SUBSTITUTED-6-FLUORO-1,4-DIHYDRO-4-OXO-QUINOLINE-3-CARBOXYLIC ACID COMPOUNDS USEFUL AS ANTIBACTERIAL AGENTS | SYNPHAR LABORATORIES, INC. (CA) | 1992-06-25 | — | — | WO | disclosed |