Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ACP3 | P15309 | 1/20 | 0.53 |
| ▸ | MIF | P14174 | 2/20 | 0.53 |
| ▸ | IDO1 | P14902 | 2/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 4/20 | 0.50 |
| ▸ | HTR2C | P28335 | 3/20 | 0.50 |
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28093819 | 0.98 | TAAR1 (0.61) | TAAR1HDAC1HDAC8MEN1KMT2A | |
| SCHEMBL1044827 | 0.95 | TAAR1 (0.61) | TAAR1HDAC1HDAC8MEN1KMT2A | |
| SCHEMBL2952807 | 0.93 | TAAR1 (0.59) | TAAR1HDAC1HDAC8MEN1KMT2A | |
| SCHEMBL1047618 | 0.93 | TAAR1 (0.59) | TAAR1HDAC1HDAC8MEN1KMT2A | |
| SCHEMBL30525290 | 0.89 | TAAR1 (0.67) | TAAR1HDAC1HDAC8MEN1KMT2A | |
| SCHEMBL156739 | 0.89 | TAAR1 (0.67) | TAAR1HDAC1HDAC8MEN1KMT2A | |
| SCHEMBL12702506 | 0.86 | TAAR1 (0.59) | TAAR1HDAC1HDAC8MEN1KMT2A | |
| SCHEMBL27956999 | 0.85 | TAAR1 (0.48) | TAAR1HDAC1HDAC8MEN1KMT2A | |
| SCHEMBL10453795 | 0.84 | TAAR1 (0.53) | TAAR1HDAC1HDAC8MEN1KMT2A | |
| SCHEMBL11383498 | 0.83 | TAAR1 (0.65) | TAAR1HDAC1HDAC8MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122059830-A | Cinacalcet hydrochloride and preparation method thereof | 江苏永安制药有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-119350167-A | Preparation method of cinacalcet hydrochloride crystal form I | 江苏永安制药有限公司 | 2025-01-24 | — | — | CN | claimed |
| CN-111153832-B | Preparation method of cinacalcet impurity | 广州九植医药科技有限公司 | 2022-02-25 | — | — | CN | claimed |
| CN-111153832-A | Preparation method of cinacalcet impurity | 广州九植医药科技有限公司 | 2020-05-15 | — | — | CN | claimed |
| CN-106831324-A | A kind of preparation method of m-trifluoromethylphenyl propyl alcohol | 四川什邡市三高生化实业有限公司 | 2017-06-13 | — | — | CN | claimed |
| EP-2403823-B1 | PROCESS FOR THE PREPARATION OF CINACALCET AND SALTS THEREOF, AND INTERMEDIATES FOR USE IN THE PROCESS | CIPLA LTD (IN) | 2015-10-21 | — | — | EP | claimed |
| CN-103958456-B | Prepare the method for cinacalcet | ZENTIVA, K.S. (CZ) | 2015-10-21 | — | — | CN | claimed |
| CN-104892428-A | Preparation method of cinacalcet hydrochloride | NANJING CHENYI BIOLOG TECHNOLOGY CO LTD | 2015-09-09 | — | — | CN | claimed |
| CN-104892356-A | Preparation method for 3-(trifluoromethyl)benzenepropanol | CHANGZHOU SUNLIGHT PHARM CO LTD | 2015-09-09 | — | — | CN | claimed |
| CN-103449989-A | Synthesis method of m-trifluoromethyl benzenepropanal | UNIV ZHEJIANG TECHNOLOGY | 2013-12-18 | — | — | CN | claimed |
| US-8575393-B2 | Process for the preparation of cinacalcet and salts thereof, and intermediates for use in the process | CIPLA LIMITED (IN) | 2013-11-05 | — | — | US | claimed |
| WO-2013075679-A1 | A METHOD OF PRODUCING CINACALCET | ZENTIVA, K.S. (CZ) | 2013-05-30 | — | — | WO | claimed |
| CN-103044267-A | Preparation method of high-purity cinacalcet hydrochloride | CHINA RESOURCES SAIKE PHARMACEUTICAL CO LTD | 2013-04-17 | — | — | CN | claimed |
| US-20120053362-A1 | Process for the Preparation of Cinacalcet and Salts Thereof, and Intermediates for Use in the Process | CIPLA LIMITED (IN) | 2012-03-01 | — | — | US | claimed |
| EP-2403823-A2 | PROCESS FOR THE PREPARATION OF CINACALCET AND SALTS THEREOF, AND INTERMEDIATES FOR USE IN THE PROCESS | Cipla Limited (IN) | 2012-01-11 | — | — | EP | claimed |
| WO-2010100429-A1 | PROCESS FOR THE PREPARATION OF CINACALCET AND SALTS THEREOF, AND INTERMEDIATES FOR USE IN THE PROCESS | CIPLA LIMITED (IN) | 2010-09-10 | — | — | WO | claimed |
| CN-122059830-A | Cinacalcet hydrochloride and preparation method thereof | 江苏永安制药有限公司 | 2026-05-19 | — | — | CN | disclosed |
| CN-122059830-A | Cinacalcet hydrochloride and preparation method thereof | 江苏永安制药有限公司 | 2026-05-19 | — | — | CN | disclosed |
| EP-0046590-A2 | Phen(alk)oxy-substituted oxirane-carboxylic acids, process for their preparation, their use and drugs containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1982-03-03 | — | — | EP | disclosed |
| EP-0025192-A2 | Substituted oxirane carboxylic acids, process for their preparation, their use and medicines containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1981-03-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053362-A1 | Process for the Preparation of Cinacalcet and Salts Thereof, and Intermediates for Use in the Process | CA4, CA9, SLC28A1 | TAAR1 1199/4885HDAC1 4312/4885HDAC8 4339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.