Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.72 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.46 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.44 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8132372 | 0.86 | KDM4E (0.71) | KDM4ECLEC4MMAPTCYP1A2CYP3A4 | |
| SCHEMBL10878556 | 0.85 | CLEC4M (0.71) | KDM4ECLEC4MMAPTCYP1A2CYP3A4 | |
| SCHEMBL5133700 | 0.85 | CLEC4M (0.71) | KDM4ECLEC4MMAPTCYP1A2CYP3A4 | |
| SCHEMBL4742144 | 0.84 | KDM4E (1.00) | KDM4ECLEC4MMAPTCYP1A2CYP3A4 | |
| SCHEMBL774558 | 0.83 | CLEC4M (0.76) | KDM4ECLEC4MMAPTCYP1A2CYP3A4 | |
| SCHEMBL6692156 | 0.82 | CLEC4M (0.67) | KDM4ECLEC4MMAPTCYP1A2CYP3A4 | |
| SCHEMBL1126279 | 0.80 | CLEC4M (0.78) | KDM4ECLEC4MMAPTCYP1A2CYP3A4 | |
| SCHEMBL28287784 | 0.80 | CLEC4M (0.82) | KDM4ECLEC4MMAPTCYP1A2CYP3A4 | |
| SCHEMBL22492440 | 0.78 | CLEC4M (0.80) | KDM4ECLEC4MMAPTCYP1A2CYP3A4 | |
| SCHEMBL1244789 | 0.78 | CLEC4M (0.80) | KDM4ECLEC4MMAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1009748-A1 | 3-ALKYLPYRROLO 3,2-$i(c)]QUINOLINE DERIVATIVES | Korea Research Institute of Chemical Technology (KR) | 2000-06-21 | — | — | EP | disclosed |
| WO-2000001696-A1 | 3-ALKYLPYRROLO[3,2-c]QUINOLINE DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2000-01-13 | — | — | WO | disclosed |