Tyrosine

Tyrosine

SCHEMBL8134263

NC(=O)CC(N)C(=O)O.NC(=O)CCC(N)C(=O)O.NC(Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.67
ALOX15 P16050 3/20 0.53
BLM P54132 1/20 0.53
PMP22 Q01453 1/20 0.53
KMT2A Q03164 1/20 0.53
PTGS1 P23219 3/20 0.49
ALPI P09923 1/20 0.49
PKM P14618 1/20 0.49
XIAP P98170 1/20 0.49
TPH1 P17752 1/20 0.47
HIF1A Q16665 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
KDM4E B2RXH2 1/20 0.47
USP2 O75604 1/20 0.47
EGFR P00533 1/20 0.47
LCK P06239 1/20 0.47
FYN P06241 1/20 0.47
ADORA3 P0DMS8 1/20 0.47
HTR2A P28223 1/20 0.47
PTGS2 P35354 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyrosine SCHEMBL8134269 1.00 SLC7A5 (0.67) SLC7A5ALOX15BLMPMP22KMT2A
Tyrosine SCHEMBL26977377 0.94 SLC7A5 (0.75) SLC7A5ALOX15BLMPMP22KMT2A
Tyrosine SCHEMBL8392474 0.94 SLC7A5 (0.75) SLC7A5ALOX15BLMPMP22KMT2A
Tyrosine SCHEMBL26977416 0.94 SLC7A5 (0.75) SLC7A5ALOX15BLMPMP22KMT2A
Tyrosine SCHEMBL1537412 0.94 SLC7A5 (0.75) SLC7A5ALOX15BLMPMP22KMT2A
Tyrosine SCHEMBL6046832 0.94 SLC7A5 (0.75) SLC7A5ALOX15BLMPMP22KMT2A
Tyrosine SCHEMBL26977409 0.94 SLC7A5 (0.75) SLC7A5ALOX15BLMPMP22KMT2A
Tyrosine SCHEMBL1580792 0.94 SLC7A5 (0.75) SLC7A5ALOX15BLMPMP22KMT2A
Tyrosine SCHEMBL6376056 0.94 SLC7A5 (0.75) SLC7A5ALOX15BLMPMP22KMT2A
Tyrosine SCHEMBL7758503 0.91 SLC7A5 (0.80) SLC7A5ALOX15PMP22KMT2APTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000001820-A2 NUCLEIC ACID MOLECULES ENCODING NUCLEAR HORMONE RECEPTOR COACTIVATORS, AND USES THEREOF THE ROCKFELLER UNIVERSITY (US) 2000-01-13 WO disclosed