Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 15/20 | 0.47 |
| ▸ | PPARA | Q07869 | 14/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8133755 | 0.97 | KDR (0.50) | KDRPTPN1FFAR1PPARGPPARA | |
| SCHEMBL8124586 | 0.94 | KDR (0.53) | KDRPTPN1FFAR1PPARGPPARA | |
| SCHEMBL8123842 | 0.93 | KDR (0.52) | KDRPTPN1FFAR1PPARGPPARA | |
| SCHEMBL8133574 | 0.87 | KDR (0.59) | KDRPTPN1FFAR1PPARGPPARA | |
| SCHEMBL8128837 | 0.83 | KDR (0.66) | KDRPTPN1FFAR1PPARGPPARA | |
| SCHEMBL6959746 | 0.83 | FFAR1 (0.67) | KDRFFAR1PPARGPPARAMAPT | |
| SCHEMBL8132144 | 0.82 | KDR (0.48) | KDRPTPN1FFAR1PPARGPPARA | |
| SCHEMBL8132495 | 0.82 | KDR (0.48) | KDRPTPN1FFAR1PPARGPPARA | |
| SCHEMBL8696457 | 0.81 | KDR (0.60) | KDRPTPN1FFAR1PPARGPPARA | |
| SCHEMBL8131858 | 0.79 | KDR (0.48) | KDRPTPN1FFAR1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733631-B1 | Benzofuran derivates useful as hypoglycemic and hypolidemic agents | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-07-12 | — | — | EP | disclosed |
| US-5723479-A | ANTILIPEMIC AGENTS AND ANTIGLYCEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-03 | — | — | US | disclosed |
| EP-0733631-A1 | Benzofuran derivates useful as hypoglycemic and hypolidemic agents | Takeda Chemical Industries, Ltd. (JP) | 1996-09-25 | — | — | EP | disclosed |