Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 19/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7514299 | 1.00 | TACR1 (0.84) | TACR1 | |
| SCHEMBL7554409 | 1.00 | TACR1 (0.84) | TACR1 | |
| Hydrochloric Acid SCHEMBL7552964 | 0.99 | TACR1 (0.84) | TACR1 | |
| Hydrochloric Acid SCHEMBL7552970 | 0.99 | TACR1 (0.84) | TACR1 | |
| SCHEMBL8197202 | 0.98 | TACR1 (0.83) | TACR1 | |
| SCHEMBL6577603 | 0.98 | TACR1 (0.83) | TACR1 | |
| Hydrochloric Acid SCHEMBL6581407 | 0.97 | TACR1 (0.83) | TACR1 | |
| SCHEMBL7523974 | 0.93 | TACR1 (0.73) | TACR1 | |
| Hydrochloric Acid SCHEMBL7560810 | 0.92 | TACR1 (0.73) | TACR1 | |
| Hydrochloric Acid SCHEMBL7560807 | 0.92 | TACR1 (0.73) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1028957-A1 | PIPERIDINE DERIVATIVES AND THEIR USE AS TACHYKININ ANTAGONISTS | MERCK SHARP & DOHME LTD. (GB) | 2000-08-23 | — | — | EP | disclosed |
| WO-1999024423-A1 | PIPERIDINE DERIVATIVES AND THEIR USE AS TACHYKININ ANTAGONISTS | MERCK SHARP & DOHME LIMITED (GB) | 1999-05-20 | — | — | WO | disclosed |