Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 8/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8135699 | 1.00 | QPCT (0.44) | QPCTNAMPTP2RX7HRH2GPR35 | |
| SCHEMBL8142433 | 0.89 | HRH2 (0.48) | QPCTNAMPTP2RX7HRH2 | |
| SCHEMBL8142436 | 0.89 | HRH2 (0.48) | QPCTNAMPTP2RX7HRH2 | |
| SCHEMBL8134099 | 0.83 | QPCT (0.47) | QPCTNAMPTGPR35LMNAMAPT | |
| SCHEMBL8134103 | 0.83 | QPCT (0.47) | QPCTNAMPTGPR35LMNAMAPT | |
| SCHEMBL8135713 | 0.82 | NAMPT (0.40) | QPCTNAMPTP2RX7HRH2 | |
| SCHEMBL8135718 | 0.82 | NAMPT (0.40) | QPCTNAMPTP2RX7HRH2 | |
| SCHEMBL4260986 | 0.80 | QPCT (0.44) | QPCTNAMPTGPR35LMNAMAPT | |
| SCHEMBL4260989 | 0.80 | QPCT (0.44) | QPCTNAMPTGPR35LMNAMAPT | |
| SCHEMBL7758049 | 0.80 | QPCT (0.44) | QPCTNAMPTGPR35LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6147098-A | USEFUL IN THE TREATMENT OF DISEASES OF THE CENTRAL NERVOUS SYSTEM, CARDIOVASCULAR SYSTEM, PULMONARY SYSTEM, GASTROINTESTINAL SYSTEM AND ENDOCRINOLOGIC SYSTEM | NOVO NORDISK A/S (DK) | 2000-11-14 | — | — | US | claimed |
| US-6147098-A | USEFUL IN THE TREATMENT OF DISEASES OF THE CENTRAL NERVOUS SYSTEM, CARDIOVASCULAR SYSTEM, PULMONARY SYSTEM, GASTROINTESTINAL SYSTEM AND ENDOCRINOLOGIC SYSTEM | NOVO NORDISK A/S (DK) | 2000-11-14 | — | — | US | disclosed |