Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8136389 | 1.00 | SRD5A1 (0.45) | SRD5A1SRD5A2 | |
| SCHEMBL916376 | 0.91 | SRD5A1 (0.49) | SRD5A1SRD5A2 | |
| SCHEMBL917557 | 0.90 | SRD5A1 (0.46) | SRD5A1SRD5A2 | |
| SCHEMBL8139828 | 0.90 | SRD5A1 (0.45) | SRD5A1SRD5A2 | |
| SCHEMBL8139829 | 0.90 | SRD5A1 (0.45) | SRD5A1SRD5A2 | |
| SCHEMBL916826 | 0.89 | SRD5A1 (0.45) | SRD5A1SRD5A2 | |
| SCHEMBL8132557 | 0.87 | SRD5A1 (0.44) | SRD5A1SRD5A2 | |
| SCHEMBL8132563 | 0.87 | SRD5A1 (0.44) | SRD5A1SRD5A2 | |
| SCHEMBL8139825 | 0.86 | SRD5A1 (0.46) | SRD5A1SRD5A2 | |
| SCHEMBL8139822 | 0.86 | SRD5A1 (0.46) | SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143887-A | REACTING A 16-METHYLSULFONATE-4-AZA-ANDROSTANONES WITH HYDROXY SUBSTITUTED AROMATIC OR HETEROAROMATIC COMPOUND AND CESIUM CARBONATE IN PRESENCE OF A POLAR APROTIC SOLVENT | MERCK & CO., INC. (US) | 2000-11-07 | — | — | US | disclosed |
| WO-1999058551-A1 | PROCESS FOR THE STEREOSELECTIVE SYNTHESIS OF 16-SUBSTITUTED-4-AZA-ANDROSTANONES | MERCK & CO., INC. (US) | 1999-11-18 | — | — | WO | disclosed |