Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 8/20 | 0.54 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.54 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.48 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.48 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8136569 | 1.00 | CYSLTR1 (0.54) | CYSLTR1CYSLTR2ABCC1MEN1ABCC3 | |
| SCHEMBL8138011 | 0.88 | CYSLTR1 (0.53) | CYSLTR1CYSLTR2ABCC1MEN1ABCC3 | |
| SCHEMBL8138020 | 0.88 | CYSLTR1 (0.53) | CYSLTR1CYSLTR2ABCC1MEN1ABCC3 | |
| SCHEMBL27352935 | 0.87 | CYSLTR1 (0.54) | CYSLTR1CYSLTR2ABCC1MEN1ABCC3 | |
| SCHEMBL13513030 | 0.86 | CYSLTR1 (0.59) | CYSLTR1CYSLTR2ABCC1MEN1ABCC3 | |
| SCHEMBL14843401 | 0.86 | CYSLTR1 (0.53) | CYSLTR1CYSLTR2ABCC1MEN1ABCC3 | |
| SCHEMBL14843400 | 0.86 | CYSLTR1 (0.53) | CYSLTR1CYSLTR2ABCC1MEN1ABCC3 | |
| SCHEMBL7496760 | 0.85 | CYSLTR2 (0.68) | CYSLTR1CYSLTR2MEN1KMT2A | |
| SCHEMBL7496756 | 0.85 | CYSLTR2 (0.68) | CYSLTR1CYSLTR2MEN1KMT2A | |
| SCHEMBL626120 | 0.84 | CYSLTR1 (0.54) | CYSLTR1CYSLTR2ABCC1MEN1ABCC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6011033-A | ANTILEUKOTRIENIC ACTION AND ANTIHISTAMINIC ACTION | KOWA CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0469833-B1 | N-Benzyl-Indoles, processes for their preparation and pharmaceutical compositions containing them | LILLY CO ELI (GB) | 1999-09-08 | — | — | EP | disclosed |
| CN-1040108-C | Pharmaceutical compounds | LILLY INDUSTRIES LTD (GB) | 1998-10-07 | — | — | CN | disclosed |
| EP-0799826-A1 | Heteroaryl substituted phenylene derivatives, their preparation and their use as leukotriene receptor antagonists | KOWA CO. LTD. (JP) | 1997-10-08 | — | — | EP | disclosed |
| EP-0533695-B1 | IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY | PFIZER (US) | 1994-10-05 | — | — | EP | disclosed |
| US-5322847-A | Inhibit platelet activating factor, block leukotriene D4 receptors | PFIZER INC. (US) | 1994-06-21 | — | — | US | disclosed |
| US-5281593-A | Pharmaceuticals | LILLY INDUSTRIES LIMITED (GB) | 1994-01-25 | — | — | US | disclosed |
| EP-0533695-A1 | IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY. | PFIZER (US) | 1993-03-31 | — | — | EP | disclosed |
| CN-1061413-A | Medicinal compound | LILLY INDUSTRIES LTD (GB) | 1992-05-27 | — | — | CN | disclosed |
| EP-0469833-A1 | N-Benzyl-Indoles, processes for their preparation and pharmaceutical compositions containing them | LILLY INDUSTRIES LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| WO-1991017163-A1 | IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY | PFIZER INC. (US) | 1991-11-14 | — | — | WO | disclosed |