Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.54 |
| ▸ | F2 | P00734 | 12/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.50 |
| ▸ | F11 | P03951 | 2/20 | 0.50 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.50 |
| ▸ | F9 | P00740 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.50 |
| ▸ | PLAT | P00750 | 1/20 | 0.50 |
| ▸ | F7 | P08709 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | MASP2 | O00187 | 1/20 | 0.45 |
| ▸ | F12 | P00748 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8145574 | 0.92 | CYP3A4 (0.57) | CYP3A4F2PRSS1F11KLKB1 | |
| SCHEMBL4207051 | 0.89 | CYP3A4 (0.56) | CYP3A4F2PRSS1F11KLKB1 | |
| SCHEMBL4199134 | 0.89 | CYP3A4 (0.56) | CYP3A4F2PRSS1F11KLKB1 | |
| Hydrochloric Acid SCHEMBL4193516 | 0.89 | CYP3A4 (0.55) | CYP3A4F2PRSS1F11KLKB1 | |
| Hydrochloric Acid SCHEMBL4202887 | 0.89 | CYP3A4 (0.55) | CYP3A4F2PRSS1F11KLKB1 | |
| SCHEMBL8151392 | 0.88 | CYP3A4 (0.51) | CYP3A4F2PRSS1F11KLKB1 | |
| SCHEMBL8150982 | 0.85 | CYP3A4 (0.57) | CYP3A4F2PRSS1F11KLKB1 | |
| SCHEMBL6079191 | 0.85 | F2 (0.60) | CYP3A4F2PRSS1F11KLKB1 | |
| SCHEMBL6919938 | 0.84 | CYP3A4 (0.57) | CYP3A4F2PRSS1F11KLKB1 | |
| SCHEMBL6919000 | 0.84 | CYP3A4 (0.57) | CYP3A4F2PRSS1F11KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009004383-A2 | AZA-BICYCLOHEXANE COMPOUNDS USEFUL AS ANTICOAGULANTS | ASTRAZENECA AB (SE) | 2009-01-08 | — | — | WO | disclosed |