Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.76 |
| ▸ | FLT1 | P17948 | 20/20 | 0.76 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7126427 | 0.91 | EGFR (0.78) | EGFRFLT1KDR | |
| SCHEMBL7117692 | 0.88 | EGFR (0.74) | EGFRFLT1KDR | |
| SCHEMBL7117826 | 0.86 | EGFR (0.84) | EGFRFLT1KDR | |
| SCHEMBL7126213 | 0.86 | EGFR (1.00) | EGFRFLT1KDR | |
| SCHEMBL7127085 | 0.86 | EGFR (0.85) | EGFRFLT1KDR | |
| SCHEMBL7123659 | 0.86 | EGFR (0.81) | EGFRFLT1KDR | |
| SCHEMBL7115515 | 0.85 | EGFR (0.79) | EGFRFLT1KDR | |
| SCHEMBL7118436 | 0.85 | EGFR (0.97) | EGFRFLT1KDR | |
| SCHEMBL7124416 | 0.85 | EGFR (0.82) | EGFRFLT1KDR | |
| SCHEMBL7123514 | 0.85 | EGFR (1.00) | EGFRFLT1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1028964-A1 | THIENOPYRIMIDINE AND THIENOPYRIDINE DERIVATIVES USEFUL AS ANTICANCER AGENTS | Pfizer Products Inc. (US) | 2000-08-23 | — | — | EP | claimed |
| WO-1999024440-A1 | THIENOPYRIMIDINE AND THIENOPYRIDINE DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER PRODUCTS INC. (US) | 1999-05-20 | — | — | WO | claimed |
| EP-1028964-A1 | THIENOPYRIMIDINE AND THIENOPYRIDINE DERIVATIVES USEFUL AS ANTICANCER AGENTS | Pfizer Products Inc. (US) | 2000-08-23 | — | — | EP | disclosed |
| WO-1999024440-A1 | THIENOPYRIMIDINE AND THIENOPYRIDINE DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER PRODUCTS INC. (US) | 1999-05-20 | — | — | WO | disclosed |