Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | HPGD | P15428 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7995766 | 0.79 | PPARG (0.51) | MAPTHPGDKMT2AL3MBTL1MEN1 | |
| SCHEMBL9827864 | 0.77 | MAPT (0.69) | MAPTHPGDKMT2AL3MBTL1MEN1 | |
| SCHEMBL7824850 | 0.76 | MAPT (1.00) | MAPTHPGDKMT2AL3MBTL1MEN1 | |
| SCHEMBL9756786 | 0.76 | MAPT (0.66) | MAPTHPGDKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11535079 | 0.74 | MAPT (0.73) | MAPTHPGDKMT2AL3MBTL1MEN1 | |
| SCHEMBL7392754 | 0.72 | MAPT (0.57) | MAPTHPGDKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1943035 | 0.67 | HPGD (0.70) | MAPTHPGDKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10062558 | 0.66 | CYP1A2 (0.50) | MAPTHPGDKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL22733876 | 0.66 | — | — | |
| SCHEMBL8007503 | 0.65 | SRD5A2 (0.52) | MAPTHPGDKMT2AL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000297086-A | HETEROARYLHYDRAZONE COMPOUND | SANKYO CO LTD | 2000-10-24 | — | — | JP | disclosed |