Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 15/20 | 0.64 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.53 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.53 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563273 | 0.88 | GRIA4 (0.67) | GRIA4GRIA2GRIA1GRIA3 | |
| SCHEMBL6563334 | 0.87 | GRIA4 (0.62) | GRIA4GRIA2GRIA1GRIA3 | |
| SCHEMBL6563303 | 0.85 | GRIA4 (0.80) | GRIA4GRIA2GRIA1GRIA3 | |
| SCHEMBL6565213 | 0.85 | GRIA4 (0.79) | GRIA4GRIA2GRIA1GRIA3 | |
| SCHEMBL6565117 | 0.84 | GRIA4 (0.77) | GRIA4GRIA2GRIA1GRIA3 | |
| SCHEMBL6563414 | 0.84 | GRIA4 (0.67) | GRIA4GRIA2GRIA1GRIA3 | |
| SCHEMBL5878156 | 0.83 | GRIA4 (0.71) | GRIA4GRIA2GRIA1GRIA3SMN1; SMN2 | |
| SCHEMBL8142024 | 0.82 | GRIA4 (0.55) | GRIA4SMN1; SMN2CA2LMNATSHR | |
| SCHEMBL6563305 | 0.81 | GRIA4 (0.92) | GRIA4GRIA2GRIA1GRIA3 | |
| SCHEMBL5877913 | 0.81 | GRIA4 (0.87) | GRIA4GRIA2GRIA1GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000006537-A1 | N-SUBSTITUTED SULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |