Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10549270 | 1.00 | BACE1 (0.35) | BACE1CYP3A4HTTSMN1; SMN2SMYD2 | |
| SCHEMBL22283784 | 0.98 | BACE1 (0.36) | BACE1CYP3A4HTTSMN1; SMN2SMYD2 | |
| SCHEMBL870869 | 0.98 | BACE1 (0.36) | BACE1CYP3A4HTTSMN1; SMN2SMYD2 | |
| SCHEMBL1139920 | 0.89 | BACE1 (0.36) | BACE1CYP3A4HTTSMN1; SMN2SMYD2 | |
| SCHEMBL1139919 | 0.89 | BACE1 (0.36) | BACE1CYP3A4HTTSMN1; SMN2SMYD2 | |
| SCHEMBL1560459 | 0.89 | BACE1 (0.36) | BACE1CYP3A4HTTSMN1; SMN2SMYD2 | |
| SCHEMBL7344125 | 0.88 | BACE1 (0.36) | BACE1 | |
| SCHEMBL7339050 | 0.88 | BACE1 (0.36) | BACE1 | |
| SCHEMBL26964687 | 0.88 | BACE1 (0.36) | BACE1 | |
| SCHEMBL7344545 | 0.88 | BACE1 (0.36) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4713320-A2 | BCAT2 INHIBITORS | Agios Pharmaceuticals, Inc. (US) | 2026-03-25 | — | — | EP | disclosed |
| WO-2024238820-A2 | BCAT2 INHIBITORS | AGIOS PHARMACEUTICALS, INC. (US) | 2024-11-21 | — | — | WO | disclosed |
| EP-4430036-A2 | BCAT2 INHIBITORS | Agios Pharmaceuticals, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| WO-2023086539-A2 | BCAT2 INHIBITORS | AGIOS PHARMACEUTICALS, INC. (US) | 2023-05-19 | — | — | WO | disclosed |
| US-6013807-A | Antitumor tetracyclic compounds | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2000-01-11 | — | — | US | disclosed |
| US-5852204-A | Pyrrolo 3,2-b-!-carbazoles and 1H 1!benzothieno 2,3-f! indoles having anti-tumor activity | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 1998-12-22 | — | — | US | disclosed |
| EP-0741729-A1 | ANTITUMOUR TETRACYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-11-13 | — | — | EP | disclosed |
| WO-1995021170-A1 | ANTITUMOUR TETRACYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-08-10 | — | — | WO | disclosed |
| US-4841071-A | 6-substituted-4-hydroxy-tetrahydropyran-2-ones | SANDOZ PHARM. CORP. (US) | 1989-06-20 | — | — | US | disclosed |
| US-4571428-A | 6-Substituted-4-hydroxy-tetrahydropyran-2-ones | SANDOZ, INC. (US) | 1986-02-18 | — | — | US | disclosed |