SCHEMBL814299

SCHEMBL814299

[c]1cc2c(c3c1CCCC3)CCCC2

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 1/20 0.31
BAD Q92934 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL551143 0.98 BCL2L1 (0.30) BCL2L1BAD
SCHEMBL7154226 0.80
SCHEMBL953469 0.70 CES1 (0.37) BCL2L1BAD
SCHEMBL3026560 0.68 BCL2L1 (0.33) BCL2L1BAD
SCHEMBL817176 0.67 TSHR (0.38) BCL2L1BADTSHR
SCHEMBL11199730 0.64 TSHR (0.39) BCL2L1BADTSHR
SCHEMBL1278375 0.64 BCL2L1 (0.52) BCL2L1BADTSHR
SCHEMBL3034213 0.64
SCHEMBL550024 0.63 BCHE (0.37) TSHR
SCHEMBL9461283 0.62 BCL2L1 (0.50) BCL2L1BADTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3925989-A1 MOLECULAR WEIGHT CONTROL OF POLYOLEFINS USING HALOGENATED BIS-PHENYLPHENOXY CATALYSTS Dow Global Technologies LLC (US) 2021-12-22 EP claimed
CN-113201084-A Molecular weight control of polyolefins using halogenated bisphenylphenoxy catalysts 陶氏环球技术有限责任公司 2021-08-03 CN claimed
CN-106687486-B Bis-biphenylphenoxy catalysts for polymerization of low molecular weight ethylene-based polymers 陶氏环球技术有限责任公司 2021-03-19 CN claimed
EP-3578578-A1 BIS-BIPHENYLPHENOXY CATALYSTS FOR POLYMERIZATION OF LOW MOLECULAR WEIGHT ETHYLENE-BASED POLYMERS Dow Global Technologies Llc (US) 2019-12-11 EP claimed
US-9975975-B2 Bis-biphenylphenoxy catalysts for polymerization of low molecular weight ethylene-based polymers DOW GLOBAL TECHNOLOGIES LLC (US) 2018-05-22 US claimed
EP-3172250-A1 BIS-BIPHENYLPHENOXY CATALYSTS FOR POLYMERIZATION OF LOW MOLECULAR WEIGHT ETHYLENE-BASED POLYMERS Dow Global Technologies Llc (US) 2017-05-31 EP claimed
US-20170137550-A1 BIS-BIPHENYLPHENOXY CATALYSTS FOR POLYMERIZATION OF LOW MOLECULAR WEIGHT ETHYLENE-BASED POLYMERS DOW GLOBAL TECHNOLOGIES LLC 2017-05-18 US claimed
US-9605098-B2 Molecular weight control of polyolefins using halogenated bis-phenylphenoxy catalysts DOW GLOBAL TECHNOLOGIES LLC (US) 2017-03-28 US claimed
EP-3013871-A1 MOLECULAR WEIGHT CONTROL OF POLYOLEFINS USING HALOGENATED BIS-PHENYLPHENOXY CATALYSTS Dow Global Technologies LLC (US) 2016-05-04 EP claimed
US-20160108156-A1 MOLECULAR WEIGHT CONTROL OF POLYOLEFINS USING HALOGENATED BIS-PHENYLPHENOXY CATALYSTS DOW GLOBAL TECHNOLOGIES LLC 2016-04-21 US claimed
WO-2016014749-A1 BIS-BIPHENYLPHENOXY CATALYSTS FOR POLYMERIZATION OF LOW MOLECULAR WEIGHT ETHYLENE-BASED POLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2016-01-28 WO claimed
WO-2014210333-A1 MOLECULAR WEIGHT CONTROL OF POLYOLEFINS USING HALOGENATED BIS-PHENYLPHENOXY CATALYSTS DOW GLOBAL TECHNOLOGIES LLC (US) 2014-12-31 WO claimed
WO-2011146044-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2011-11-24 WO claimed
CN-115298227-B Group III and lanthanide bis-phenyl-phenoxy metal-ligand complexes 陶氏环球技术有限责任公司 2024-06-04 CN disclosed
WO-2024050359-A1 GROUP III-HALIDE OR LANTHANIDE-HALIDE BIS(PHENYLPHENOXY) METAL−LIGAND COMPLEXES DOW GLOBAL TECHNOLOGIES LLC (US) 2024-03-07 WO disclosed
WO-2024050368-A1 METHOD OF PRODUCING MULTIMODAL POLYETHYLENE USING AT LEAST ONE GROUP III-BASED OR LANTHANIDE-BASED BIPHENYLPHENOXY CATALYST DOW GLOBAL TECHNOLOGIES LLC (US) 2024-03-07 WO disclosed
EP-2491062-B1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2013-12-11 EP disclosed
WO-2013101376-A1 HYPERBRANCHED OLEFIN OIL-BASED DIELECTRIC FLUID DOW GLOBAL TECHNOLOGIES LLC (US) 2013-07-04 WO disclosed
WO-2013101375-A1 PROCESS FOR PRODUCING LOW MOLECULAR WEIGHT ETHYLENE- AND ALPHA-OLEFIN-BASED MATERIALS DOW GLOBAL TECHNOLOGIES LLC (US) 2013-07-04 WO disclosed
US-20110282018-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC 2011-11-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110282018-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR WEE2, NOTUM, WEE1 BCL2L1 2016/4885BAD 2013/4885TSHR 4494/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.