Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | C1R | P00736 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985985 | 0.85 | C1R (0.47) | TP53C1RMAPTALDH1A1LMNA | |
| SCHEMBL25350286 | 0.78 | TP53 (0.49) | TP53MAPTALDH1A1LMNAHTT | |
| SCHEMBL8577911 | 0.77 | C1R (0.49) | C1RMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL25348064 | 0.77 | TP53 (0.61) | TP53MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL25349254 | 0.74 | TP53 (0.48) | TP53MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8144973 | 0.74 | HSP90AA1 (0.53) | TP53C1RMAPTALDH1A1LMNA | |
| SCHEMBL8136893 | 0.73 | TP53 (0.49) | TP53C1RMAPTALDH1A1LMNA | |
| SCHEMBL25348979 | 0.70 | TP53 (0.62) | TP53MAPTALDH1A1LMNAHTT | |
| Bromide SCHEMBL8469205 | 0.70 | TP53 (0.52) | TP53C1RMAPTLMNAKMT2A | |
| SCHEMBL8144928 | 0.69 | TP53 (0.64) | TP53MAPTALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6018047-A | GROUP Z-A-AT POSITION 10, WHERE A IS A DIVALENT ORGANIC MOIETY AND Z IS CAPABLE OF COUPLING A BIOACTIVE COMPOUND, AND AT POSITION 9 AN ESTER WHICH FORMS DIOXETANE WITH HYDROGEN PEROXIDE; USE IN HETEROGENEOUS AND HOMOGENEOUS IMMUNOASSAYS | ZOMER GIJSBERT (NL) | 2000-01-25 | — | — | US | disclosed |