Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRL | P40313 | 10/20 | 0.74 |
| ▸ | TMPRSS11D | O60235 | 3/20 | 0.68 |
| ▸ | PSMB5 | P28074 | 9/20 | 0.68 |
| ▸ | PSMB8 | P28062 | 4/20 | 0.49 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.49 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.49 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.49 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.49 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.49 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.49 |
| ▸ | PSMA4 | P25789 | 2/20 | 0.49 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.49 |
| ▸ | PSMA5 | P28066 | 2/20 | 0.49 |
| ▸ | PSMB4 | P28070 | 2/20 | 0.49 |
| ▸ | PSMB6 | P28072 | 2/20 | 0.49 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.49 |
| ▸ | PSMB3 | P49720 | 2/20 | 0.49 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.49 |
| ▸ | PSMA6 | P60900 | 2/20 | 0.49 |
| ▸ | PSMA8 | Q8TAA3 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19289284 | 1.00 | CTRL (0.74) | CTRLTMPRSS11DPSMB5PSMB8PSMB11 | |
| SCHEMBL17319651 | 1.00 | CTRL (0.74) | CTRLTMPRSS11DPSMB5PSMB8PSMB11 | |
| SCHEMBL22423768 | 1.00 | CTRL (0.74) | CTRLTMPRSS11DPSMB5PSMB8PSMB11 | |
| SCHEMBL8138091 | 1.00 | CTRL (0.74) | CTRLTMPRSS11DPSMB5PSMB8PSMB11 | |
| SCHEMBL15479562 | 0.95 | CTRL (0.69) | CTRLTMPRSS11DPSMB5PSMB8PSMB11 | |
| SCHEMBL14538219 | 0.94 | CTRL (0.84) | CTRLTMPRSS11DPSMB5PSMB8PSMB11 | |
| SCHEMBL8148206 | 0.94 | CTRL (0.84) | CTRLTMPRSS11DPSMB5PSMB8PSMB11 | |
| SCHEMBL19289283 | 0.94 | CTRL (0.84) | CTRLTMPRSS11DPSMB5PSMB8PSMB11 | |
| SCHEMBL8136773 | 0.92 | CTRL (0.63) | CTRLTMPRSS11DPSMB5 | |
| SCHEMBL8123171 | 0.89 | CTRL (0.62) | CTRLTMPRSS11DPSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140782-A2 | COMPOUNDS FOR ENZYME INHIBITION | PROTEOLIX, INC. (US) | 2008-11-20 | — | — | WO | disclosed |