Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 7/20 | 0.77 |
| ▸ | CASP1 | P29466 | 3/20 | 0.51 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.48 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8143937 | 1.00 | SRC (0.77) | SRCCASP1CASP8MCHR1CCR3 | |
| SCHEMBL8148754 | 0.89 | SRC (0.70) | SRCCASP1CASP8MCHR1CCR3 | |
| SCHEMBL8148759 | 0.89 | SRC (0.70) | SRCCASP1CASP8MCHR1CCR3 | |
| SCHEMBL8149119 | 0.88 | SRC (0.71) | SRCCASP1CASP8MCHR1CCR3 | |
| SCHEMBL8149116 | 0.88 | SRC (0.71) | SRCCASP1CASP8MCHR1CCR3 | |
| SCHEMBL8143902 | 0.87 | SRC (1.00) | SRCCASP1CASP8MCHR1 | |
| SCHEMBL8143905 | 0.87 | SRC (1.00) | SRCCASP1CASP8MCHR1 | |
| SCHEMBL8149500 | 0.87 | SRC (0.70) | SRCCASP1CASP8MCHR1CCR3 | |
| SCHEMBL8135922 | 0.86 | SRC (0.77) | SRCCASP1CASP8MCHR1CCR3 | |
| SCHEMBL8143728 | 0.81 | SRC (0.67) | SRCCASP1CASP8MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000005246-A1 | THIOAZEPINONE DERIVATIVES, PREPARATION METHOD AND INTERMEDIATES THEREFOR, USE AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | HOECHST MARION ROUSSEL (FR) | 2000-02-03 | — | — | WO | claimed |
| WO-2000005246-A1 | THIOAZEPINONE DERIVATIVES, PREPARATION METHOD AND INTERMEDIATES THEREFOR, USE AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | HOECHST MARION ROUSSEL (FR) | 2000-02-03 | — | — | WO | disclosed |