Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8144157 | 1.00 | CYP2D6 (0.50) | CYP2D6MC4RKMT2AMEN1HSD17B10 | |
| SCHEMBL852612 | 1.00 | CYP2D6 (0.50) | CYP2D6MC4RKMT2AMEN1HSD17B10 | |
| SCHEMBL14675361 | 0.74 | CYP2D6 (0.42) | CYP2D6MC4RKMT2AMEN1HSD17B10 | |
| SCHEMBL12846188 | 0.68 | CYP2D6 (0.56) | CYP2D6MC4RKMT2AMEN1HSD17B10 | |
| SCHEMBL852613 | 0.68 | CYP2D6 (0.56) | CYP2D6MC4RKMT2AMEN1HSD17B10 | |
| SCHEMBL20034096 | 0.68 | CYP2D6 (0.56) | CYP2D6MC4RKMT2AMEN1HSD17B10 | |
| SCHEMBL10035306 | 0.68 | CYP2D6 (0.56) | CYP2D6MC4RKMT2AMEN1HSD17B10 | |
| SCHEMBL5355369 | 0.67 | CYP2D6 (0.74) | CYP2D6MC4RKMT2AMEN1HSD17B10 | |
| SCHEMBL16226061 | 0.67 | CYP2D6 (1.00) | CYP2D6MC4ROPRM1OPRD1OPRK1 | |
| SCHEMBL7009772 | 0.67 | CYP2D6 (0.54) | CYP2D6MC4RKMT2AMEN1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025496-A | Process for preparing heterocyclic carbenes | CELANESE GMBH (DE) | 2000-02-15 | — | — | US | disclosed |