SCHEMBL8145369

SCHEMBL8145369

O=C1/C=C\C(=O)OCCOCCO1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.50
CA9 Q16790 2/20 0.50
LMNA P02545 4/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
CRHBP P24387 2/20 0.43
CRHR2 Q13324 2/20 0.43
HTT P42858 2/20 0.43
TTR P02766 1/20 0.38
GAA P10253 3/20 0.35
ALDH1A1 P00352 1/20 0.35
TP53 P04637 1/20 0.35
TSHR P16473 1/20 0.35
MAPT P10636 4/20 0.34
BLM P54132 1/20 0.34
KDM4E B2RXH2 3/20 0.33
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6738735 0.90 CA1 (0.58) CA1CA9LMNASMN1; SMN2CRHBP
SCHEMBL5198695 0.90 CA1 (0.58) CA1CA9LMNASMN1; SMN2CRHBP
SCHEMBL7042020 0.90 CA1 (0.58) CA1CA9LMNASMN1; SMN2CRHBP
Water SCHEMBL27829315 0.87 CA1 (0.55) CA1CA9LMNAALDH1A1TP53
Maleic Anhydride SCHEMBL28308581 0.81 CA1 (0.38) CA1CA9LMNASMN1; SMN2CRHBP
Maleic Anhydride SCHEMBL20163204 0.78 CA1 (0.39) CA1CA9LMNATTRGAA
SCHEMBL8731692 0.78 CA1 (0.52) CA1CA9LMNAALDH1A1TP53
SCHEMBL29594067 0.78 CA1 (0.52) CA1CA9LMNASMN1; SMN2ALDH1A1
SCHEMBL4554729 0.78 CA1 (0.52) CA1CA9LMNASMN1; SMN2ALDH1A1
SCHEMBL7784650 0.78 CA1 (0.52) CA1CA9LMNAALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6150437-A A FLOW CONTROL AGENT COMPRISING A GRAFT POLYMERS PREPARED BY RADICAL GRAFTING OF A POLYALKYLENE OXIDE WITH AN ETHYLENICALLY UNSATURATED ACID OR THE ANHYDRIDE THEREOF, AND THEN MODIFIED BY A PRIMARY OR SECONDARY AMINE OR ALCOHOL SKW TROSTBERG AKTIENGESELLSCHAFT (DE) 2000-11-21 US disclosed
EP-0133779-B1 IMPROVED CONTROL OF TRANSFORMATIONS WITHIN POLYMERS AND PRODUCTS THEREOF RAPRA TECHNOLOGY LIMITED (GB) 1989-12-27 EP disclosed
US-4767804-A REACTING LOW MOLECULAR WEIGHT THIOL- OR CARBOXYL-TERMINATED POLYMER WITH METAL COMPOUND RUBBER BANDS AND PLASTIC RESEARCH ASSOCIATION OF GREAT BRITAIN (GB) 1988-08-30 US disclosed
EP-0133779-A2 Improved control of transformations within polymers and products thereof RAPRA TECHNOLOGY LIMITED (GB) 1985-03-06 EP disclosed
US-4110244-A Photochromic plastic material AMERICAN OPTICAL CORPORATION (US) 1978-08-29 US disclosed
US-4049846-A Photochromic plastic materials AMERICAN OPTICAL CORPORATION (US) 1977-09-20 US disclosed