SCHEMBL814654

SCHEMBL814654

C=C(c1ccccc1)c1cccc(C(=C)c2ccccc2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
ATM Q13315 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
MAPT P10636 1/20 0.43
HTT P42858 1/20 0.43
GFER P55789 1/20 0.43
HSD17B10 Q99714 1/20 0.43
GPR55 Q9Y2T6 1/20 0.43
CHEK1 O14757 1/20 0.40
KDR P35968 1/20 0.40
CES2 O00748 2/20 0.39
CES1 P23141 2/20 0.39
DAO P14920 1/20 0.39
TSHR P16473 1/20 0.39
NAPRT Q6XQN6 1/20 0.39
ALDH1A1 P00352 1/20 0.39
KMO O15229 1/20 0.38
MAOA P21397 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21811989 0.97 MEN1 (0.50) MEN1KMT2AATMTDP1L3MBTL1
SCHEMBL8538380 0.92 MEN1 (0.54) MEN1KMT2AATMTDP1L3MBTL1
SCHEMBL4015060 0.89 MEN1 (0.48) MEN1KMT2AATMTDP1L3MBTL1
Benzene SCHEMBL28340939 0.88 MEN1 (0.61) MEN1KMT2AATMTDP1L3MBTL1
SCHEMBL7930063 0.88 MEN1 (0.61) MEN1KMT2AATMTDP1L3MBTL1
SCHEMBL3844822 0.88 MEN1 (0.61) MEN1KMT2AATMTDP1L3MBTL1
Benzene SCHEMBL9731493 0.88 MEN1 (0.61) MEN1KMT2AATMTDP1L3MBTL1
SCHEMBL26736 0.88 MEN1 (0.61) MEN1KMT2AATMTDP1L3MBTL1
SCHEMBL29010802 0.86 MEN1 (0.54) MEN1KMT2AATMTDP1L3MBTL1
SCHEMBL717315 0.85 CA12 (0.56) MEN1KMT2ATDP1MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 347 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3093302-B1 MODIFIED CONJUGATED DIENE-BASED POLYMER, MODIFIED RUBBER COMPOSITION CONTAINING SAME, AND METHOD FOR PREPARING MODIFIED CONJUGATED DIENE-BASED POLYMER LG CHEMICAL LTD (KR) 2019-10-09 EP claimed
US-9834619-B2 Modified conjugated diene-based polymer, modified rubber composition containing same, and method for preparing modified conjugated diene-based polymer LG CHEM, LTD. (KR) 2017-12-05 US claimed
US-20160355612-A1 MODIFIED CONJUGATED DIENE-BASED POLYMER, MODIFIED RUBBER COMPOSITION CONTAINING SAME, AND METHOD FOR PREPARING MODIFIED CONJUGATED DIENE-BASED POLYMER LG CHEM, LTD. (KR) 2016-12-08 US claimed
EP-3093302-A1 MODIFIED CONJUGATED DIENE-BASED POLYMER, MODIFIED RUBBER COMPOSITION CONTAINING SAME, AND METHOD FOR PREPARING MODIFIED CONJUGATED DIENE-BASED POLYMER LG Chem, Ltd. (KR) 2016-11-16 EP claimed
US-7825199-B1 mediated by transition metal complex in redox reaction of atom transfer Atom Transfer Coupling Reaction to/from initiator or dormant polymer and growing active polymer chain ends; transition metal held in close conjunction with a solid support; salt containing a soluble organic counterion; styrene graft CARNEGIE MELLON UNIVERSITY (US) 2010-11-02 US claimed
US-20040171779-A1 Redox systems; using transition metal complex catalysts; atom transfer radical polymerization CARNEGIE MELLON UNIVERSITY (A NON-PROFIT PENNSYLVANIA ORGANIZATION) 2004-09-02 US claimed
US-6767976-B2 POLYMERIZING METHACRYLIC ESTER OR ACRYLIC ESTER ANIONICALLY, USING A POLYMERIZATION INITIATOR COMPRISING ADDITION REACTION PRODUCT OF CONJUGATED DIENE COMPOUND AND ORGANIC ALKALI METAL COMPOUND AND TERTIARY ORGANOALUMINUM COMPOUND KURARAY CO., LTD. (JP) 2004-07-27 US claimed
US-6462143-B1 PRIMARILY FUNCTIONALIZED ANIONIC POLYMERS WHICH ARE MADE USING MULTI-LITHIUM INITIATORS ARE PREVENTED FROM GELLING, OR GEL IS REMOVED BY ADDITION OF TRIALKYL ALUMINUM COMPOUND KRATON POLYMERS US LLC 2002-10-08 US claimed
EP-1171496-A1 CATALYTIC PROCESSES FOR THE CONTROLLED POLYMERIZATION OF FREE RADICALLY (CO)POLYMERIZABLE MONOMERS AND FUNCTIONAL POLYMERIC SYSTEMS PREPARED THEREBY CARNEGIE-MELLON UNIVERSITY (US) 2002-01-16 EP claimed
EP-1042369-A1 GEL-FREE PROCESS FOR MAKING FUNCTIONALIZED ANIONICALLY POLYMERIZED POLYMERS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 2000-10-11 EP claimed
WO-2000056795-A1 CATALYTIC PROCESSES FOR THE CONTROLLED POLYMERIZATION OF FREE RADICALLY (CO)POLYMERIZABLE MONOMERS AND FUNCTIONAL POLYMERIC SYSTEMS PREPARED THEREBY CARNEGIE MELLON UNIVERSITY (US) 2000-09-28 WO claimed
WO-1999040121-A1 GEL-FREE PROCESS FOR MAKING FUNCTIONALIZED ANIONICALLY POLYMERIZED POLYMERS SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 1999-08-12 WO claimed
US-4982029-A Method for the direct preparation of olefins from ketones and Grignard reagents THE DOW CHEMICAL COMPANY (US) 1991-01-01 US claimed
US-4956415-A MEMBRANES, THICKENERS, BLOCK POLYMERIZATION FOLLOWED BY COUPLING THE DOW CHEMICAL COMPANY (US) 1990-09-11 US claimed
US-4885343-A ANIONICALLY POLYMERIZABLE MONOMER AND COUPLING AGENTS THE DOW CHEMICAL COMPANY (US) 1989-12-05 US claimed
US-4839430-A COUPLING WITH M/BISPHENYLETHENYL/--BENZENE THE DOW CHEMICAL COMPANY (US) 1989-06-13 US claimed
US-12515174-B2 Articles including an isoporous membrane disposed on a porous substrate and methods of making the same SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-01-06 US disclosed
US-12460082-B2 Counter tapered thermoplastic elastomers DYNASOL ELASTÓMEROS, S.A. DE C.V. (MX) 2025-11-04 US disclosed
EP-0001977-A1 Soluble multifunctional lithium containing initiators and their use in a process for polymerisation THE DOW CHEMICAL COMPANY (US) 1979-05-30 EP disclosed
EP-0001977-A1 Soluble multifunctional lithium containing initiators and their use in a process for polymerisation THE DOW CHEMICAL COMPANY (US) 1979-05-30 EP disclosed