Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 17/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8152601 | 0.92 | GRM2 (0.65) | GRM2 | |
| SCHEMBL8138805 | 0.92 | GRM2 (0.61) | GRM2 | |
| SCHEMBL8152638 | 0.89 | GRM2 (0.53) | GRM2 | |
| SCHEMBL8151833 | 0.87 | GRM2 (0.52) | GRM2 | |
| SCHEMBL8151836 | 0.87 | GRM2 (0.53) | GRM2 | |
| SCHEMBL8152885 | 0.87 | GRM2 (0.57) | GRM2 | |
| SCHEMBL8150845 | 0.86 | GRM2 (0.51) | GRM2 | |
| SCHEMBL8146242 | 0.86 | GRM2 (0.48) | GRM2 | |
| SCHEMBL8152303 | 0.85 | GRM2 (0.50) | GRM2 | |
| SCHEMBL8151961 | 0.85 | GRM2 (0.47) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6028090-A | Adhesion receptor antagonists III | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-02-22 | — | — | US | disclosed |
| US-5561148-A | Adhesion receptor antagonists III | MERCK PATENT GESELLSCHAFT MIT BESHRANKTER HAFTUNG (DE) | 1996-10-01 | — | — | US | disclosed |