Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 3/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | RARB | P10826 | 10/20 | 0.48 |
| ▸ | RARA | P10276 | 2/20 | 0.48 |
| ▸ | RARG | P13631 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | TACR2 | P21452 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1906454 | 0.91 | MPL (0.49) | HSD17B10TSHRRARBRARARARG | |
| SCHEMBL4900272 | 0.91 | HTR2A (0.55) | HSD17B10HTR2ASLC6A2SLC6A4HTR2C | |
| SCHEMBL4895814 | 0.91 | HTR2A (0.55) | HSD17B10HTR2ASLC6A2SLC6A4HTR2C | |
| SCHEMBL4887234 | 0.91 | HTR2A (0.55) | HSD17B10HTR2ASLC6A2SLC6A4HTR2C | |
| SCHEMBL30369240 | 0.91 | HTR2A (0.55) | HSD17B10HTR2ASLC6A2SLC6A4HTR2C | |
| SCHEMBL4898274 | 0.91 | HTR2A (0.55) | HSD17B10HTR2ASLC6A2SLC6A4HTR2C | |
| SCHEMBL2930325 | 0.89 | HTR2A (0.52) | HSD17B10HTR2ASLC6A2SLC6A4HTR2C | |
| SCHEMBL31228811 | 0.89 | HTR2A (0.52) | HSD17B10HTR2ASLC6A2SLC6A4HTR2C | |
| SCHEMBL5683706 | 0.88 | TSHR (0.66) | HSD17B10TSHRHTR2ASLC6A2SLC6A4 | |
| SCHEMBL5686753 | 0.88 | TSHR (0.66) | HSD17B10TSHRHTR2ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000178211-A | FLUORENE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION INCLUDING THE SAME | CHISSO CORP | 2000-06-27 | — | — | JP | disclosed |