Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.56 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9202510 | 0.85 | TSHR (0.63) | TSHRPRSS1PRSS2PRSS3MAPT | |
| SCHEMBL2767396 | 0.84 | TSHR (0.72) | TSHRMAPTRAB9ANPC1POLB | |
| SCHEMBL2889619 | 0.83 | TSHR (0.65) | TSHRMAPTRAB9ANPC1POLB | |
| SCHEMBL28050912 | 0.80 | TSHR (0.77) | TSHRMAPTRAB9ANPC1POLB | |
| SCHEMBL16955993 | 0.80 | TSHR (0.71) | TSHRMAPTRAB9ANPC1POLB | |
| SCHEMBL18838994 | 0.80 | TSHR (0.61) | TSHRMAPTRAB9ANPC1POLB | |
| SCHEMBL1611926 | 0.80 | PRSS1 (0.58) | PRSS1MAPTALDH1A1GAAL3MBTL1 | |
| SCHEMBL1829461 | 0.80 | TSHR (0.61) | TSHRMAPTRAB9ANPC1POLB | |
| SCHEMBL31378091 | 0.80 | TSHR (0.61) | TSHRMAPTRAB9ANPC1POLB | |
| SCHEMBL264768 | 0.79 | TSHR (1.00) | TSHRMAPTRAB9ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116399-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-17 | — | — | US | disclosed |