Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 15/20 | 0.48 |
| ▸ | FNTB | P49356 | 14/20 | 0.48 |
| ▸ | PGGT1B | P53609 | 5/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5131468 | 0.90 | FNTA (0.51) | FNTAFNTBPGGT1BCYP19A1NR1H4 | |
| SCHEMBL445939 | 0.90 | FNTA (0.51) | FNTAFNTBPGGT1BCYP19A1NR1H4 | |
| Hydrochloric Acid SCHEMBL8160943 | 0.89 | FNTA (0.51) | FNTAFNTBPGGT1BCYP19A1NR1H4 | |
| Hydrochloric Acid SCHEMBL8541088 | 0.89 | FNTA (0.51) | FNTAFNTBPGGT1BCYP19A1NR1H4 | |
| SCHEMBL3687066 | 0.87 | FNTA (0.59) | FNTAFNTBPGGT1BCYP19A1GRM2 | |
| SCHEMBL445626 | 0.87 | FNTA (0.59) | FNTAFNTBPGGT1BCYP19A1GRM2 | |
| Trifluoroacetic Acid SCHEMBL8147178 | 0.84 | FNTA (0.54) | FNTAFNTBPGGT1BCYP19A1 | |
| Hydrochloric Acid SCHEMBL8485271 | 0.83 | FNTA (0.37) | FNTAFNTBPGGT1BCYP19A1 | |
| SCHEMBL3685047 | 0.83 | FNTA (0.49) | FNTAFNTBPGGT1BCYP19A1 | |
| SCHEMBL3499936 | 0.83 | FNTA (0.49) | FNTAFNTBPGGT1BCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6060038-A | Radiolabeled farnesyl-protein transferase inhibitors | MERCK & CO., INC. (US) | 2000-05-09 | — | — | US | disclosed |