Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHOC | P08134 | 3/20 | 0.36 |
| ▸ | RHOA | P61586 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | USP2 | O75604 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5200933 | 0.85 | GAA (0.36) | RHOCRHOAALDH1A1TSHRGAA | |
| SCHEMBL8147682 | 0.82 | TDP1 (0.37) | RHOCRHOAALDH1A1KDM4ETSHR | |
| SCHEMBL8147679 | 0.82 | TDP1 (0.37) | RHOCRHOAALDH1A1KDM4ETSHR | |
| SCHEMBL8147257 | 0.80 | TSHR (0.33) | RHOCRHOAALDH1A1KDM4ETSHR | |
| SCHEMBL8147256 | 0.80 | TSHR (0.33) | RHOCRHOAALDH1A1KDM4ETSHR | |
| SCHEMBL8155286 | 0.78 | NPC1 (0.44) | — | |
| SCHEMBL17393677 | 0.76 | KDM4E (0.39) | KDM4E | |
| SCHEMBL959562 | 0.76 | KMT2A (0.37) | ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL29870686 | 0.76 | KMT2A (0.37) | ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL119998 | 0.76 | KMT2A (0.37) | ALDH1A1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057352-A | CONTROLLING PLANT DISEASES CAUSED BY FUNGAL PLANT PATHOGENS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-05-02 | — | — | US | disclosed |