Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | EDNRA | P25101 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | SNCA | P37840 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7638891 | 0.86 | CYP1A2 (0.49) | MAPTMAPK1TDP1CYP1A2GLA | |
| SCHEMBL5712321 | 0.85 | CYP1A2 (0.65) | MAPTMAPK1TDP1CYP1A2GLA | |
| SCHEMBL5712304 | 0.85 | CYP1A2 (0.65) | MAPTMAPK1TDP1CYP1A2GLA | |
| SCHEMBL7636448 | 0.84 | CYP1A2 (0.47) | MAPTMAPK1TDP1CYP1A2GLA | |
| SCHEMBL7637830 | 0.84 | CYP1A2 (0.47) | MAPTMAPK1TDP1CYP1A2GLA | |
| SCHEMBL8154644 | 0.84 | MAPT (0.46) | MAPTMAPK1TDP1CYP1A2CYP3A4 | |
| SCHEMBL9404176 | 0.84 | CYP1A2 (0.47) | MAPTMAPK1TDP1CYP1A2GLA | |
| SCHEMBL7631992 | 0.82 | CYP1A2 (0.50) | MAPTMAPK1TDP1CYP1A2GLA | |
| SCHEMBL7632973 | 0.81 | CYP1A2 (0.47) | MAPTMAPK1TDP1CYP1A2GLA | |
| SCHEMBL8148425 | 0.80 | CYP1A2 (0.73) | MAPTMAPK1TDP1CYP1A2GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6028116-A | Substituted condensation products of 1H-indenyl-hydroxyalkanes with aldehydes for neoplasia | CELL PATHWAYS, INC. (US) | 2000-02-22 | — | — | US | disclosed |