Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8150627 | 0.99 | EGLN1 (0.32) | EGLN1CYP19A1CNR2 | |
| SCHEMBL8157295 | 0.88 | EGLN1 (0.33) | EGLN1CYP19A1 | |
| SCHEMBL8156812 | 0.87 | CYP19A1 (0.31) | EGLN1CYP19A1 | |
| Hydrochloric Acid SCHEMBL8150165 | 0.86 | CYP19A1 (0.31) | EGLN1CYP19A1 | |
| SCHEMBL8149036 | 0.84 | EGLN1 (0.33) | EGLN1CYP19A1 | |
| SCHEMBL8149818 | 0.84 | EGLN1 (0.35) | EGLN1CYP19A1 | |
| SCHEMBL8156634 | 0.81 | S1PR1 (0.33) | EGLN1CYP19A1 | |
| SCHEMBL8151901 | 0.80 | CYP19A1 (0.34) | EGLN1CYP19A1 | |
| Hydrochloric Acid SCHEMBL8148673 | 0.80 | S1PR1 (0.33) | EGLN1CYP19A1 | |
| SCHEMBL8142506 | 0.79 | CYP19A1 (0.38) | EGLN1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6077853-A | Inhibitors of farnesyl-protein transferase | MERCK & CO., INC. (US) | 2000-06-20 | — | — | US | disclosed |