SCHEMBL8148917

SCHEMBL8148917

C=CC(=O)OCCOC(=O)/C=C/c1ccc(C(F)(F)F)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.55
HDAC3 O15379 1/20 0.51
ADAM17 P78536 1/20 0.51
HDAC1 Q13547 1/20 0.51
HDAC2 Q92769 1/20 0.51
HDAC10 Q969S8 1/20 0.51
HDAC11 Q96DB2 1/20 0.51
HDAC8 Q9BY41 1/20 0.51
HDAC6 Q9UBN7 1/20 0.51
HDAC5 Q9UQL6 1/20 0.51
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
MET P08581 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
CA5B Q9Y2D0 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17570318 1.00 CYP1A2 (0.55) CYP1A2HDAC3ADAM17HDAC1HDAC2
SCHEMBL20090792 0.88 CA12 (0.61) CYP1A2CA12CA1METCA4
SCHEMBL8152935 0.84 CYP1A2 (0.50) CYP1A2HDAC3ADAM17HDAC1HDAC2
SCHEMBL16705742 0.84 CYP1A2 (0.43) CYP1A2HDAC3ADAM17HDAC1HDAC2
SCHEMBL8146929 0.83 CYP2D6 (0.48) HDAC1HDAC8CA12CA1MET
SCHEMBL4580984 0.82 CA12 (0.72) CA12CA1METCA4CA6
SCHEMBL6395001 0.82 CA12 (0.72) CA12CA1METCA4CA6
SCHEMBL20090793 0.82 TSHR (0.61) CA12CA1METCA4CA6
SCHEMBL6789739 0.82 APP (0.61) CYP1A2CYP1A1CYP1B1MAOB
SCHEMBL22882052 0.82 CYP1A2 (0.54) CYP1A2HDAC3ADAM17HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10838302-B2 Cross-linkable fluorinated photopolymer ORTHOGONAL, INC. (US) 2020-11-17 US disclosed
US-20200301276-A1 CROSS-LINKABLE FLUORINATED PHOTOPOLYMER ORTHOGONAL, INC. (US) 2020-09-24 US disclosed
WO-2020163762-A1 FLUOROPOLYMER RESIST STRUCTURES HAVING AN UNDERCUT PROFILE ORTHOGONAL, INC. (US) 2020-08-13 WO disclosed
US-10739680-B2 Cross-linkable fluorinated photopolymer ORTHOGONAL, INC. (US) 2020-08-11 US disclosed
EP-3238288-B1 PHOTOLITHOGRAPHIC PATTERNING OF ELECTRONIC DEVICES ORTHOGONAL INC (US) 2020-07-29 EP disclosed
US-20190227436-A1 CROSS-LINKABLE FLUORINATED PHOTOPOLYMER ORTHOGONAL, INC. (US) 2019-07-25 US disclosed
US-10289000-B2 Cross-linkable fluorinated photopolymer ORTHOGONAL, INC. (US) 2019-05-14 US disclosed
US-9991114-B2 Photolithographic patterning of electronic devices ORTHOGONAL, INC. (US) 2018-06-05 US disclosed
US-9991114-B2 Photolithographic patterning of electronic devices ORTHOGONAL, INC. (US) 2018-06-05 US disclosed
US-9958778-B2 Cross-linkable fluorinated photopolymer ORTHOGONAL, INC. (US) 2018-05-01 US disclosed
US-20160349614-A1 CROSS-LINKABLE FLUORINATED PHOTOPOLYMER ORTHOGONAL, INC. 2016-12-01 US disclosed
US-9217926-B2 Method of patterning a base layer ORTHOGONAL, INC. (US) 2015-12-22 US disclosed
US-9217926-B2 Method of patterning a base layer ORTHOGONAL, INC. (US) 2015-12-22 US disclosed
WO-2015089062-A1 PATTERNING FUNCTIONAL MATERIALS ORTHOGONAL, INC. (US) 2015-06-18 WO disclosed
US-20150140289-A1 METHOD OF PATTERNING A BIORESORBABLE MATERIAL ORTHOGONAL, INC. 2015-05-21 US disclosed
US-20150140729-A1 METHOD OF PATTERNING A BASE LAYER ORTHOGONAL, INC. 2015-05-21 US disclosed
US-20150140729-A1 METHOD OF PATTERNING A BASE LAYER ORTHOGONAL, INC. 2015-05-21 US disclosed
US-20150140289-A1 METHOD OF PATTERNING A BIORESORBABLE MATERIAL ORTHOGONAL, INC. 2015-05-21 US disclosed
US-RE36625-E Linear and cyclic polymers or oligomers having a photoreactive ethene group ROLIC AG (CH) 2000-03-21 US disclosed
US-5539074-A LIQUID CRYSTAL POLYMERS ON SILICA FOR LIGHT SENSITIVE ELEMENTS HOFFMANN-LA ROCHE INC. (US) 1996-07-23 US disclosed