SCHEMBL8149147

SCHEMBL8149147

CCCCCOC(C)CCc1ccc(C(=O)O)cc1

nearest known ligand 0.60

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
RARB P10826 9/20 0.57
MEN1 O00255 1/20 0.56
ALDH1A1 P00352 1/20 0.56
RARA P10276 1/20 0.56
MAPT P10636 1/20 0.56
MTOR P42345 1/20 0.56
KMT2A Q03164 1/20 0.56
TP53 P04637 1/20 0.54
TSHR P16473 1/20 0.54
PLA2G4B P0C869 6/20 0.52
PLA2G4A P47712 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8149112 0.91 RARB (0.50) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL9257180 0.89 RARB (0.61) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL9260988 0.89 RARB (0.57) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL9257178 0.89 RARB (0.61) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL9260994 0.89 RARB (0.57) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL9252643 0.87 RARB (0.56) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL8163169 0.87 TP53 (0.58) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL9260814 0.85 RARB (0.50) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL14685935 0.82 ESR1 (0.57) ALDH1A1MAPTTP53
SCHEMBL3033446 0.82 KCNH2 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0806417-B1 Novel optically active benzene derivatives, process for producing the same and liquid-crystalline composition containing said derivatives as liquid-crystalline compound and light switching elements SUMITOMO CHEMICAL CO (JP) 2000-03-08 EP disclosed
US-5693251-A LIQUID CRYSTAL DISPLAYS; HIGH SPEED RESPONSE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-02 US disclosed
EP-0806417-A1 Novel optically active benzene derivatives, process for producing the same and liquid-crystalline composition containing said derivatives as liquid-crystalline compound and light switching elements SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-11-12 EP disclosed
US-5389293-A Light switches SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-02-14 US disclosed
EP-0360622-A2 Novel optically active benzene derivatives, process for producing the same and liquid-crystalline composition containing said derivatives as liquid-crystalline compound and light switching elements SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-03-28 EP disclosed