Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 2/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8140777 | 1.00 | EPHX1 (0.38) | EPHX1TP53ANPEPERAP2KDM4E | |
| SCHEMBL8637949 | 0.98 | EPHX1 (0.38) | EPHX1TP53ANPEPERAP2KDM4E | |
| SCHEMBL8643107 | 0.86 | ANPEP (0.40) | EPHX1TP53ANPEPERAP2KDM4E | |
| SCHEMBL8152905 | 0.86 | ANPEP (0.40) | EPHX1TP53ANPEPERAP2KDM4E | |
| SCHEMBL8645781 | 0.84 | ANPEP (0.37) | EPHX1TP53ANPEPERAP2KDM4E | |
| SCHEMBL8642104 | 0.82 | ANPEP (0.46) | EPHX1TP53ANPEPERAP2KDM4E | |
| SCHEMBL8155014 | 0.82 | ANPEP (0.46) | EPHX1TP53ANPEPERAP2KDM4E | |
| SCHEMBL8152956 | 0.79 | — | — | |
| SCHEMBL8153189 | 0.74 | CA1 (0.33) | EPHX1ANPEPERAP2CA1CA2 | |
| SCHEMBL8153328 | 0.71 | GRIN2D (0.31) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000013690-A1 | EXOCYCLIC-PHOSPHOETHANOLAMINES | CLARION PHARMACEUTICALS, INC. (US) | 2000-03-16 | — | — | WO | disclosed |
| US-5804569-A | ANTIINFLAMMATORY, ANTIARRHYMIC AND LOCAL ANESTHETIC AGENT | CLARION PHARMACEUTICALS INC. (US) | 1998-09-08 | — | — | US | disclosed |