Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4631375 | 1.00 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL4631371 | 1.00 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL4631370 | 0.92 | EDNRA (0.84) | EDNRAEDNRB | |
| SCHEMBL4631372 | 0.92 | EDNRA (0.84) | EDNRAEDNRB | |
| SCHEMBL8149350 | 0.87 | EDNRA (0.76) | EDNRAEDNRB | |
| SCHEMBL4631568 | 0.85 | EDNRA (0.73) | EDNRAEDNRB | |
| SCHEMBL4631567 | 0.85 | EDNRA (0.73) | EDNRAEDNRB | |
| SCHEMBL4632048 | 0.84 | EDNRA (0.72) | EDNRAEDNRB | |
| SCHEMBL4631430 | 0.83 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL4631436 | 0.83 | EDNRA (1.00) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1048657-A1 | Thienyl-, furyl-, pyrrolyl- and biphenylsulfonamides and derivatives thereof that modulate the activity of endothelin | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2000-11-02 | — | — | EP | disclosed |