Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 7/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | USP8 | P40818 | 1/20 | 0.36 |
| ▸ | USP7 | Q93009 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8155633 | 0.83 | ESR2 (0.59) | ESR2ESR1MEN1KMT2AKDM4E | |
| SCHEMBL1168040 | 0.77 | MEN1 (0.50) | ESR2ESR1MEN1KMT2AKDM4E | |
| SCHEMBL5448639 | 0.76 | ESR1 (0.58) | ESR2ESR1MEN1KMT2AKDM4E | |
| SCHEMBL29616926 | 0.76 | ESR1 (0.58) | ESR2ESR1MEN1KMT2AKDM4E | |
| SCHEMBL8151936 | 0.75 | AKR1C1 (0.63) | ESR2ESR1MEN1KMT2AMAPT | |
| SCHEMBL8150327 | 0.74 | USP8 (0.36) | ESR2KDM4EMAPTSMN1; SMN2PDK2 | |
| SCHEMBL30063507 | 0.74 | ESR1 (0.55) | ESR2ESR1MEN1KMT2AKDM4E | |
| SCHEMBL22452824 | 0.74 | ESR1 (0.55) | ESR2ESR1MEN1KMT2AKDM4E | |
| SCHEMBL212466 | 0.73 | KMT2A (0.43) | ESR2ESR1MEN1KMT2AKDM4E | |
| SCHEMBL7917312 | 0.73 | ESR1 (0.50) | ESR2ESR1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6051294-A | RETORT-STERILIZABLE PACKAGING MATERIALS EXHIBITING HIGH BARRIER TO OXYGEN | THE DOW CHEMICAL COMPANY (US) | 2000-04-18 | — | — | US | disclosed |
| US-5814373-A | PACKAGING OF OXYGEN SENSITIVE MATERIALS INSIDE A CONTAINER COMPRISING A THERMOPLASTIC POLYMER | DOW CHEMICAL COMPANY (US) | 1998-09-29 | — | — | US | disclosed |