Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.38 |
| ▸ | PDE4A | P27815 | 3/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1952047 | 0.85 | USP2 (0.39) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL1023279 | 0.85 | PDE4A (0.39) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL3369389 | 0.84 | PDE4D (0.38) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8247781 | 0.84 | PDE4D (0.38) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8249075 | 0.82 | PDE4D (0.36) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL1023006 | 0.81 | KDM4E (0.47) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL3370734 | 0.79 | ESR1 (0.40) | KDM4EMEN1KMT2AALDH1A1PDE4D | |
| SCHEMBL13219446 | 0.75 | RPS6KA5 (0.34) | MAPTMEN1KMT2AALDH1A1PDE4D | |
| SCHEMBL8136201 | 0.74 | ADORA1 (0.35) | KDM4EMEN1KMT2AALDH1A1KDR | |
| SCHEMBL15483504 | 0.74 | KMT2A (0.36) | KDM4EMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771454-B1 | HEPATITIS C INHIBITOR PEPTIDE ANALOGS | BOEHRINGER INGELHEIM INT (DE) | 2011-06-15 | — | — | EP | disclosed |
| WO-2009005677-A2 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2009-01-08 | — | — | WO | disclosed |