Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 4/20 | 0.51 |
| ▸ | BACE1 | P56817 | 2/20 | 0.51 |
| ▸ | SCN2A | Q99250 | 8/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 3/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8194967 | 0.89 | SCN2A (0.62) | HPGDSSCN2ANPY5RCNR2CNR1 | |
| SCHEMBL8110918 | 0.85 | BACE1 (0.46) | HPGDSBACE1SCN2ANPY5RCNR2 | |
| SCHEMBL7811963 | 0.82 | NPY5R (0.61) | SCN2ANPY5RCNR2CNR1 | |
| SCHEMBL7142281 | 0.81 | SCN2A (0.47) | HPGDSBACE1SCN2ANPY5RCNR2 | |
| SCHEMBL7179734 | 0.81 | BACE1 (0.47) | HPGDSBACE1SCN2ANPY5RCNR2 | |
| Hydrochloric Acid SCHEMBL7808457 | 0.81 | NPY5R (0.60) | SCN2ANPY5RCNR2CNR1 | |
| Hydrochloric Acid SCHEMBL7815919 | 0.81 | NPY5R (0.60) | SCN2ANPY5RCNR2CNR1 | |
| SCHEMBL7143623 | 0.80 | BACE1 (0.46) | HPGDSBACE1SCN2ANPY5RCNR2 | |
| SCHEMBL7143626 | 0.79 | BACE1 (0.45) | HPGDSBACE1SCN2ANPY5RCNR2 | |
| SCHEMBL8188950 | 0.79 | BACE1 (0.45) | HPGDSBACE1SCN2ANPY5RCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996443-A1 | CERTAIN DIARYLIMIDAZOLE DERIVATIVES; A NEW CLASS OF NPY SPECIFIC LIGANDS | NEUROGEN CORPORATION (US) | 2000-05-03 | — | — | EP | claimed |
| WO-1999001128-A1 | CERTAIN DIARYLIMIDAZOLE DERIVATIVES; A NEW CLASS OF NPY SPECIFIC LIGANDS | NEUROGEN CORPORATION (US) | 1999-01-14 | — | — | WO | claimed |