Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14732604 | 0.89 | TP53 (0.46) | TP53TDP1ALDH1A1TSHRNPC1 | |
| SCHEMBL14732600 | 0.86 | TP53 (0.43) | TP53TDP1ALDH1A1TSHRNPC1 | |
| SCHEMBL1025611 | 0.86 | TP53 (0.39) | TP53TDP1ALDH1A1TSHRFAAH | |
| SCHEMBL1025233 | 0.86 | TP53 (0.39) | TP53TDP1ALDH1A1TSHRNPC1 | |
| SCHEMBL7171513 | 0.84 | TP53 (0.48) | TP53TDP1ALDH1A1TSHRNPC1 | |
| SCHEMBL27745104 | 0.83 | TP53 (0.41) | TP53TDP1ALDH1A1TSHRNPC1 | |
| SCHEMBL7903852 | 0.83 | TDP1 (0.41) | TP53TDP1ALDH1A1TSHRNPC1 | |
| SCHEMBL7089843 | 0.83 | TP53 (0.37) | TP53TDP1ALDH1A1TSHRFAAH | |
| SCHEMBL15292597 | 0.82 | TP53 (0.40) | TP53TDP1ALDH1A1TSHRNPC1 | |
| SCHEMBL15958303 | 0.82 | TP53 (0.36) | TP53TDP1ALDH1A1TSHRACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6041157-A | Environmentally sensitive compositions of matter based on 3H-fluoren-3-ylidenes and process for making same | GOETZ FREDERICK JAMES (US) | 2000-03-21 | — | — | US | disclosed |