Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2411613 | 0.75 | CA1 (0.47) | MEN1KMT2ASMN1; SMN2CYP2D6HSD17B10 | |
| SCHEMBL2381384 | 0.74 | — | — | |
| SCHEMBL23829804 | 0.72 | MEN1 (0.31) | MEN1KMT2ACYP2D6HSD17B10 | |
| SCHEMBL13515396 | 0.70 | — | — | |
| SCHEMBL576309 | 0.70 | — | — | |
| SCHEMBL5936338 | 0.70 | — | — | |
| SCHEMBL5936327 | 0.70 | — | — | |
| SCHEMBL5427811 | 0.68 | PRSS1 (0.35) | MEN1KMT2ACYP2D6HSD17B10 | |
| SCHEMBL14563378 | 0.68 | PRSS1 (0.35) | MEN1KMT2ACYP2D6HSD17B10 | |
| SCHEMBL14563383 | 0.68 | PRSS1 (0.35) | MEN1KMT2ACYP2D6HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008119772-A1 | AMIDE DERIVATIVES AS INHIBITORS OF ASPARTYL PROTEASES | MEDIVIR AB (SE) | 2008-10-09 | — | — | WO | disclosed |