SCHEMBL8152219

SCHEMBL8152219

C=CCCCC[SiH](C)O[Si](C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.37
ALDH1A1 P00352 2/20 0.34
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27873967 0.98 TSHR (0.40) TSHRALDH1A1LMNA
SCHEMBL29013733 0.98 TSHR (0.40) TSHRALDH1A1LMNA
SCHEMBL27873970 0.98 TSHR (0.40) TSHRALDH1A1LMNA
SCHEMBL28444026 0.98 TSHR (0.40) TSHRALDH1A1LMNA
SCHEMBL29013729 0.94 TSHR (0.36) TSHRALDH1A1
SCHEMBL27924006 0.85 TSHR (0.31) TSHR
SCHEMBL29035841 0.77
SCHEMBL29013722 0.77
SCHEMBL6248571 0.77 TSHR (0.41) TSHRALDH1A1LMNA
SCHEMBL9228106 0.75 TSHR (0.44) TSHRALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111433235-B Capped double-ended organoaluminum compositions 陶氏环球技术有限责任公司 2023-06-13 CN disclosed
CN-109952324-B Blocked multi-or double-headed compositions suitable for chain shuttling and methods of making the same 陶氏环球技术有限责任公司 2023-06-09 CN disclosed
CN-102498133-B Bid-or multi-head chain shuttling agents and their use for the preparation of block copolymers DOW GLOBAL TECHNOLOGIES INC 2013-10-30 CN disclosed
CN-102498133-A Bid-or multi-head chain shuttling agents and their use for the preparation of block copolymers DOW GLOBAL TECHNOLOGIES INC 2012-06-13 CN disclosed
EP-0971992-A1 CROSS-LINKABLE COMPOUNDS, OPTIONALLY CONTAINING MQ SILICON RESINS Wacker-Chemie GmbH (DE) 2000-01-19 EP disclosed
WO-1998042789-A1 CROSS-LINKABLE COMPOUNDS, OPTIONALLY CONTAINING MQ SILICON RESINS WACKER-CHEMIE GMBH (DE) 1998-10-01 WO disclosed