SCHEMBL8152373

SCHEMBL8152373

N#C[C@@H]1CCCN1C(=O)[C@@H]1NCCC1C(=O)C[C@H]1CCc2ccccc2C1

nearest known ligand 0.64

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PREP P48147 9/20 0.64
DPP4 P27487 8/20 0.47
FAP Q12884 4/20 0.46
DPP8 Q6V1X1 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9047944 1.00 PREP (0.64) PREPDPP4FAPDPP8
SCHEMBL8146762 0.95 PREP (0.62) PREPDPP4FAPDPP8
SCHEMBL9050167 0.91 PREP (0.57) PREPDPP4FAPDPP8
SCHEMBL9049537 0.91 PREP (0.57) PREPDPP4FAPDPP8
SCHEMBL9050276 0.88 PREP (0.55) PREPDPP4FAPDPP8
SCHEMBL9048048 0.86 PREP (0.53) PREPDPP4FAPDPP8
SCHEMBL9047189 0.85 PREP (0.48) PREP
SCHEMBL9050174 0.85 PREP (0.54) PREP
SCHEMBL9048078 0.83 PREP (0.52) PREPDPP4FAPDPP8
SCHEMBL9048922 0.83 PREP (0.52) PREPDPP4FAPDPP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6017929-A Cholinesterase activator ZERIA PHARMACEUTICAL CO., LTD. (JP) 2000-01-25 US disclosed
EP-0754454-A1 CHOLINESTERASE ACTIVATOR ZERIA PHARMACEUTICAL CO., LTD. (JP) 1997-01-22 EP disclosed