Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8148590 | 0.99 | SPHK1 (0.43) | SPHK1ESR2SPHK2GRIN2DGRIN3B | |
| SCHEMBL7788400 | 0.96 | SPHK1 (0.39) | SPHK1ESR2SPHK2GRIN2DGRIN3B | |
| SCHEMBL7788622 | 0.91 | ESR2 (0.40) | SPHK1ESR2SPHK2GRIN2DGRIN3B | |
| SCHEMBL7793473 | 0.88 | SPHK1 (0.42) | SPHK1SPHK2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL8148059 | 0.87 | SPHK1 (0.44) | SPHK1SPHK2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL7792393 | 0.86 | SPHK1 (0.43) | SPHK1SPHK2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL7789266 | 0.86 | SPHK1 (0.57) | SPHK1ESR2SPHK2GRIN2DGRIN3B | |
| SCHEMBL7793030 | 0.85 | SPHK1 (0.45) | SPHK1SPHK2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL7788715 | 0.85 | SPHK1 (0.59) | SPHK1ESR2SPHK2GRIN2DGRIN3B | |
| SCHEMBL7791470 | 0.85 | SPHK1 (0.59) | SPHK1ESR2SPHK2GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6010642-A | LIGHT SCATTERING LIQUID CRYSTAL DISPLAY | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0825176-A1 | Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1998-02-25 | — | — | EP | disclosed |